Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11618317 | 0.92 | POLB (0.49) | FABP4FABP5KDM4EPOLBPKM | |
| SCHEMBL11615779 | 0.85 | KDM4E (0.45) | KDM4EPOLBPKML3MBTL1ABCB11 | |
| SCHEMBL11621960 | 0.79 | POLB (0.42) | KDM4EPOLBPKMHSD17B10L3MBTL1 | |
| SCHEMBL11613651 | 0.79 | KDM4E (0.46) | KDM4EPOLBPKMHSD17B10L3MBTL1 | |
| SCHEMBL11613646 | 0.79 | KDM4E (0.46) | KDM4EPOLBPKMHSD17B10L3MBTL1 | |
| SCHEMBL11616435 | 0.78 | PKM (0.42) | KDM4EPOLBPKMABCB11 | |
| SCHEMBL11617064 | 0.76 | GPR35 (0.49) | KDM4EPOLBPKMHSD17B10MAPK1 | |
| SCHEMBL11617342 | 0.74 | POLB (0.44) | FABP4FABP5KDM4EPOLBPKM | |
| SCHEMBL11617264 | 0.74 | KDM4E (0.44) | KDM4EHSD17B10CTNNB1 | |
| SCHEMBL8417551 | 0.71 | FABP4 (0.56) | FABP4FABP5KDM4EPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | disclosed |