Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 2/20 | 0.33 |
| ▸ | MMP16 | P51512 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162678 | 0.84 | ALDH1A1 (0.35) | ALDH1A1HSD17B10TDP1TRPV4 | |
| SCHEMBL1162496 | 0.81 | TRPV4 (0.36) | ALDH1A1HSD17B10TDP1TRPV4MMP1 | |
| SCHEMBL1415493 | 0.80 | L3MBTL1 (0.46) | ALDH1A1HSD17B10TDP1TRPV4MMP1 | |
| SCHEMBL10645229 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TDP1TRPV4MMP1 | |
| SCHEMBL8713730 | 0.77 | GABRA1 (0.39) | ALDH1A1HSD17B10L3MBTL1HTR2CCA1 | |
| SCHEMBL4455751 | 0.77 | TRPV4 (0.35) | ALDH1A1HSD17B10TDP1TRPV4 | |
| SCHEMBL10627469 | 0.77 | P2RX7 (0.37) | ALDH1A1HSD17B10TDP1TRPV4MMP1 | |
| SCHEMBL1415486 | 0.74 | TRPV4 (0.40) | ALDH1A1HSD17B10TDP1TRPV4MMP1 | |
| SCHEMBL1501176 | 0.74 | ALDH1A1 (0.34) | ALDH1A1HSD17B10TDP1TRPV4MMP1 | |
| SCHEMBL10641545 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TDP1TRPV4MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343544-B1 | Method for analyzing hemoglobin by electrophoresis | ARKRAY INC (JP) | 2015-03-11 | — | — | EP | disclosed |
| EP-1548020-B1 | SILICON COMPOUND | JNC CORP (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8702941-B2 | Method of analyzing hemoglobin by electrophoresis | ARKARY, Inc. (JP) | 2014-04-22 | — | — | US | disclosed |
| WO-2013173501-A2 | CHROMATOGRAPHIC MATERIALS | WATERS TECHNOLOGIES CORPORATION (US) | 2013-11-21 | — | — | WO | disclosed |
| WO-2013158277-A1 | METHODS FOR QUANTIFYING POLYPEPTIDES USING MASS SPECTROMETRY | WATERS TECHNOLOGIES CORPORATION (US) | 2013-10-24 | — | — | WO | disclosed |
| EP-2462188-A1 | HIGH PURITY CHROMATROGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER | Waters Technologies Corporation (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-2343544-A1 | Method for analyzing hemoglobin by electrophoresis | Arkray, Inc. (JP) | 2011-07-13 | — | — | EP | disclosed |
| US-20110155573-A1 | METHOD OF ANALYZING HEMOGLOBIN BY ELECTROPHORESIS | ARKRAY, INC. (JP) | 2011-06-30 | — | — | US | disclosed |
| WO-2011017418-A1 | HIGH PURITY CHROMATROGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER | WATERS TECHNOLOGIES CORPORATION (US) | 2011-02-10 | — | — | WO | disclosed |
| US-7294732-B2 | Cyclic polysilsequisiloxanes substituted with a group containing a sulfonyl halide, especially ahalosulfonylphenyl group; living radical polymerization initiators, particularly for preparing acrylic polymers | CHISSO CORPORATION (JP) | 2007-11-13 | — | — | US | disclosed |
| US-20050288468-A1 | Cyclic polysilsequisiloxanes substituted with a group containing a sulfonyl halide, especially ahalosulfonylphenyl group; living radical polymerization initiators, particularly for preparing acrylic polymers | JNC CORPORATION (JP) | 2005-12-29 | — | — | US | disclosed |
| EP-1548020-A1 | SILICON COMPOUND | CHISSO CORPORATION (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288468-A1 | Cyclic polysilsequisiloxanes substituted with a group containing a sulfonyl halide, especially ahalosulfonylphenyl group; living radical polymerization initiators, particularly for preparing acrylic polymers | STS, SULT1A1, SRM | ALDH1A1 384/4885HSD17B10 1153/4885TDP1 1867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.