SCHEMBL4455751

SCHEMBL4455751

CCO[Si](OCC)(OCC)C(C)c1ccccc1S(=O)(=O)Cl

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 2/20 0.35
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PTPRC P08575 1/20 0.30
CDC25B P30305 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1162496 0.83 TRPV4 (0.36) TRPV4ALDH1A1HSD17B10TDP1
SCHEMBL562866 0.80 TSHR (0.38) ALDH1A1PTPRCCDC25B
Benzene SCHEMBL28228273 0.78 TSHR (0.36) ALDH1A1
SCHEMBL1162373 0.77 ALDH1A1 (0.39) TRPV4ALDH1A1HSD17B10TDP1
SCHEMBL2763038 0.74 ADRA2A (0.33) ALDH1A1
SCHEMBL2526800 0.73 SLC6A2 (0.31) ALDH1A1
SCHEMBL1415493 0.73 L3MBTL1 (0.46) TRPV4ALDH1A1HSD17B10TDP1
SCHEMBL8087531 0.72 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1
SCHEMBL1765857 0.72 TSHR (0.53) ALDH1A1HSD17B10
SCHEMBL28332142 0.72 CA1 (0.41) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871668-B2 Immobilized lewis acid catalysts coated with ionic liquids and use thereof JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2014-10-28 US disclosed
EP-1997555-B1 IMMOBILIZED LEWIS ACID CATALYSTS COATED WITH IONIC LIQUIDS AND USE THEREOF JAPAN SCIENCE & TECH AGENCY (JP) 2013-02-27 EP disclosed
US-20090318729-A1 IMMOBILIZED LEWIS ACID CATALYSTS COATED WITH IONIC LIQUIDS AND USE THEREOF JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2009-12-24 US disclosed
EP-1997555-A1 IMMOBILIZED LEWIS ACID CATALYSTS COATED WITH IONIC LIQUIDS AND USE THEREOF Japan Science and Technology Agency (JP) 2008-12-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090318729-A1 IMMOBILIZED LEWIS ACID CATALYSTS COATED WITH IONIC LIQUIDS AND USE THEREOF SELL, LCT, LDHA TRPV4 4033/4885ALDH1A1 731/4885HSD17B10 4283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.