SCHEMBL116469

SCHEMBL116469

CCCCCCCCCCCCCCCCCCCC(CCCCCCCCCCCCCCCCCC)CNC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
EPHX1 P07099 1/20 0.46
TSHR P16473 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP3A4 P08684 1/20 0.44
DNM1 Q05193 2/20 0.40
THRB P10828 1/20 0.40
LCK P06239 1/20 0.40
PPARD Q03181 1/20 0.40
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
S1PR2 O95136 5/20 0.39
S1PR1 P21453 5/20 0.39
S1PR3 Q99500 5/20 0.39
S1PR4 O95977 4/20 0.39
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH4 P08319 1/20 0.39
ADH7 P40394 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12320427 1.00 LMNA (0.52) LMNAEPHX1TSHRALDH1A1CYP3A4
SCHEMBL24219829 1.00 LMNA (0.52) LMNAEPHX1TSHRALDH1A1CYP3A4
SCHEMBL10489059 1.00 LMNA (0.52) LMNAEPHX1TSHRALDH1A1CYP3A4
Bromide SCHEMBL9619162 0.98 LMNA (0.50) LMNAEPHX1TSHRALDH1A1CYP3A4
SCHEMBL20718611 0.98 LMNA (0.50) LMNAEPHX1TSHRALDH1A1CYP3A4
SCHEMBL22857636 0.95 LMNA (0.48) LMNAEPHX1TSHRALDH1A1CYP3A4
SCHEMBL24850078 0.95 ALDH1A1 (0.50) LMNAEPHX1TSHRALDH1A1CYP3A4
SCHEMBL2179490 0.93 LMNA (0.44) LMNAEPHX1TSHRALDH1A1CYP3A4
SCHEMBL25992548 0.91 ALDH1A1 (0.58) LMNAEPHX1TSHRALDH1A1CYP3A4
SCHEMBL18426286 0.91 ALDH1A1 (0.58) LMNAEPHX1TSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605325-B2 Hair styling compositions for improving the elongation of hair curls L'OREAL (FR) 2026-04-21 US disclosed
US-12599546-B2 Hair treatment compositions, kits thereof, and methods thereof L'OREAL (FR) 2026-04-14 US disclosed
US-12589065-B2 Hair care system, hair care method and use of a hair care system L'OREAL (FR) 2026-03-31 US disclosed
US-12551422-B2 Compositions and methods for styling the hair L'ORÉAL (FR) 2026-02-17 US disclosed
US-20260000583-A1 COSMETIC KIT WITH A CLEANSING STICK, DISPENSING CONTAINER, AND CUTTING DEVICE L'OREAL (FR) 2026-01-01 US disclosed
US-20250367104-A1 SOLIDIFIED GEL AND METHODS FOR CLEANSING SKIN L'OREAL (FR) 2025-12-04 US disclosed
US-20250367103-A1 SOLIDIFIED GEL AND METHODS FOR CLEANSING SKIN L'OREAL (FR) 2025-12-04 US disclosed
EP-4633589-A1 HAIR TREATMENT COMPOSITIONS THAT IMPART SHINE AND LUSTER L'OREAL (FR) 2025-10-22 EP disclosed
US-20250302716-A1 HAIR TREATMENT SERUM AND METHOD OF USE L'OREAL (FR) 2025-10-02 US disclosed
US-12383483-B2 Compositions and methods for styling the hair L'OREAL (FR) 2025-08-12 US disclosed
WO-2010069501-A1 COSMETIC COMPOSITION FOR HAIR AND SCALP KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-06-24 WO disclosed
EP-2196178-A1 Cosmetic composition for hair and scalp KPSS-Kao Professional Salon Services GmbH (DE) 2010-06-16 EP disclosed
WO-2010060601-A1 BLEACHING/HIGHLIGHTING COMPOSITION KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-06-03 WO disclosed
EP-2191812-A1 Bleaching/Highlighting composition KPSS-Kao Professional Salon Services GmbH (DE) 2010-06-02 EP disclosed
WO-2010046077-A2 COLOURING COMPOSITION KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-04-29 WO disclosed
WO-2010046080-A2 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-04-29 WO disclosed
EP-2177204-A1 Colouring composition KPSS-Kao Professional Salon Services GmbH (DE) 2010-04-21 EP disclosed
EP-2177205-A1 Composition for the permanent shaping of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2010-04-21 EP disclosed
WO-2010025894-A2 CONDITIONING COMPOSITION FOR HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-03-11 WO disclosed
EP-2161016-A1 Conditioning composition for hair KPSS-Kao Professional Salon Services GmbH (DE) 2010-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367104-A1 SOLIDIFIED GEL AND METHODS FOR CLEANSING SKIN CUTA, DSG1, POLG LMNA 2806/4885EPHX1 2040/4885TSHR 4644/4885
US-12605325-B2 Hair styling compositions for improving the elongation of hair curls SGMS1, SGMS2, SGPL1 LMNA 498/4885EPHX1 3529/4885TSHR 2285/4885
US-12551422-B2 Compositions and methods for styling the hair DPM1, PIK3C3, SMURF1 LMNA 281/4885EPHX1 3663/4885TSHR 2988/4885
US-12589065-B2 Hair care system, hair care method and use of a hair care system ASH2L, ALG3, PLOD3 LMNA 478/4885EPHX1 3028/4885TSHR 2630/4885
US-12599546-B2 Hair treatment compositions, kits thereof, and methods thereof EBP, FHIT, BRDT LMNA 220/4885EPHX1 3956/4885TSHR 3668/4885
US-20260000583-A1 COSMETIC KIT WITH A CLEANSING STICK, DISPENSING CONTAINER, AND CUTTING DEVICE CUTA, PRKDC, PRKACG LMNA 1260/4885EPHX1 2295/4885TSHR 3423/4885
US-20250367103-A1 SOLIDIFIED GEL AND METHODS FOR CLEANSING SKIN CUTA, DSG1, POLG LMNA 2806/4885EPHX1 2040/4885TSHR 4644/4885
US-12383483-B2 Compositions and methods for styling the hair SGMS1, SGMS2, DPM1 LMNA 467/4885EPHX1 3503/4885TSHR 3112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.