Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517662 | 0.82 | INSR (0.44) | CYP1A2CYP3A4CYP2C19PTPN1KMO | |
| SCHEMBL11664183 | 0.82 | ALDH1A1 (0.48) | CYP1A2CYP3A4CYP2C19ALDH1A1LMNA | |
| SCHEMBL5476170 | 0.74 | ACHE (0.41) | CYP1A2CYP3A4CYP2C19PTPN1ALDH1A1 | |
| SCHEMBL11748071 | 0.73 | MAPT (0.53) | CYP1A2CYP3A4CYP2C19PTPN1ALDH1A1 | |
| SCHEMBL8390924 | 0.71 | INSR (0.80) | INSRGAAGFERMAPTAPOBEC3G | |
| SCHEMBL8390923 | 0.71 | INSR (0.80) | INSRGAAGFERMAPTAPOBEC3G | |
| SCHEMBL5675183 | 0.69 | INSR (0.53) | CYP3A4ALDH1A1LMNAINSRTDP1 | |
| SCHEMBL28429355 | 0.68 | ALDH1A1 (0.75) | CYP1A2CYP3A4CYP2C19ALDH1A1TDP1 | |
| SCHEMBL11732864 | 0.66 | HSP90AA1 (0.46) | CYP1A2CYP3A4CYP2C19ALDH1A1LMNA | |
| SCHEMBL10619263 | 0.66 | ALDH1A1 (0.53) | CYP1A2CYP3A4CYP2C19ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4089747-A | OXIDATION OF DYE-PROVIDING MATERIALS, A SULFONYL HYDRAZONE AND A COUPLER OR A TRIARYLIMIDAZOLE | EASTMAN KODAK COMPANY (US) | 1978-05-16 | — | — | US | disclosed |