Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | CETP | P11597 | 2/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1434360 | 0.82 | EPHX1 (0.46) | NPSR1EPHX1HTR2AHTR2CHTR2B | |
| SCHEMBL30781560 | 0.81 | NPSR1 (0.45) | NPSR1EPHX1OPRM1CES2KDM4E | |
| Acetic Acid SCHEMBL3291394 | 0.80 | EPHX1 (0.44) | NPSR1EPHX1OPRM1CES2KDM4E | |
| SCHEMBL1434358 | 0.80 | NPSR1 (0.44) | NPSR1EPHX1CETPCES2HDAC6 | |
| SCHEMBL18546019 | 0.79 | NPSR1 (0.43) | NPSR1CYP1A2HDAC6KDM4ETAS1R3 | |
| SCHEMBL5598191 | 0.79 | NPSR1 (0.40) | NPSR1CYP1A2CYP2C9ALOX15KDM4E | |
| SCHEMBL5598193 | 0.79 | NPSR1 (0.40) | NPSR1CYP1A2CYP2C9ALOX15KDM4E | |
| SCHEMBL29600101 | 0.79 | NPSR1 (0.40) | NPSR1CYP1A2CYP2C9ALOX15KDM4E | |
| SCHEMBL2107552 | 0.79 | NPSR1 (0.44) | NPSR1EPHX1CETPHTR2AHTR2C | |
| SCHEMBL15016758 | 0.77 | ALDH1A1 (0.43) | NPSR1HTR2AHTR2BCYP3A4ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234674-B1 | FLUID OIL-IN-WATER SUNSCREEN EMULSIONS CONTAINING A SELECTED GEMINI SURFACTANT AND A CROSSLINKED COPOLYMER OF METHACRYLIC ACID AND OF ETHYL ACRYLATE | L'ORÉAL (FR) | 2017-03-29 | — | — | EP | disclosed |
| US-20140287005-A1 | PHOTOPROTECTIVE COMPOSITION CONTAINING AN UNMODIFIED GELLING STARCH AND POLYAMIDE PARTICLES | L'OREAL (FR) | 2014-09-25 | — | — | US | disclosed |
| US-8535647-B2 | Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor | L'OREAL (FR) | 2013-09-17 | — | — | US | disclosed |
| US-8241613-B2 | Sun protection compositions comprising semi-crystalline polymers and hollow latex particles | L'OREAL (FR) | 2012-08-14 | — | — | US | disclosed |
| US-20110027202-A1 | FLUID OIL-IN-WATER SUNSCREEN EMULSIONS CONTAINING GEMINI SURFACTANTS AND A CROSSLINKED COPOLYMER OF METHACRYLIC ACID AND OF C1-C4 ALKYL ACRYLATE | L'OREAL (FR) | 2011-02-03 | — | — | US | disclosed |
| US-20100086502-A1 | Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor | L'OREAL (FR) | 2010-04-08 | — | — | US | disclosed |
| US-20090041691-A1 | Sun protection compositions comprising semi-crystalline polymers and hollow latex particles | L'OREAL (FR) | 2009-02-12 | — | — | US | disclosed |
| US-20090016971-A1 | Aqueous fluid photoprotective compositions comprising tertiary-amide-terminated polyamide polymers | L'OREAL (FR) | 2009-01-15 | — | — | US | disclosed |
| US-20090018200-A1 | COMPOSITION CONTAINING A PHENANTHRENOL | L'OREAL (FR) | 2009-01-15 | — | — | US | disclosed |
| US-20080159970-A1 | KIT COMPRISING SILICONE COMPOUNDS AND A COSMETIC AND/OR DERMATOLOGICAL ACTIVE AGENT | L'OREAL (FR) | 2008-07-03 | — | — | US | disclosed |
| US-20080160088-A1 | COMPOSITION CONTAINING HYDROXYAPATITE AND A CALCIUM SALT | L'OREAL (FR) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090041691-A1 | Sun protection compositions comprising semi-crystalline polymers and hollow latex particles | CTSA, CUTA, MCM7 | NPSR1 4158/4885EPHX1 3607/4885CETP 651/4885 |
| US-20080159970-A1 | KIT COMPRISING SILICONE COMPOUNDS AND A COSMETIC AND/OR DERMATOLOGICAL ACTIVE AGENT | KRT18, CUTA, KIT | NPSR1 4102/4885EPHX1 1682/4885CETP 1749/4885 |
| US-20100086502-A1 | Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor | NOTUM, DDT, FDFT1 | NPSR1 4016/4885EPHX1 1078/4885CETP 2222/4885 |
| US-20110027202-A1 | FLUID OIL-IN-WATER SUNSCREEN EMULSIONS CONTAINING GEMINI SURFACTANTS AND A CROSSLINKED COPOLYMER OF METHACRYLIC ACID AND OF C1-C4 ALKYL ACRYLATE | C1S, TP53, CDC25C | NPSR1 4474/4885EPHX1 1243/4885CETP 1811/4885 |
| US-20090016971-A1 | Aqueous fluid photoprotective compositions comprising tertiary-amide-terminated polyamide polymers | CUTA, ATP5F1A, ATP5F1B | NPSR1 3003/4885EPHX1 3438/4885CETP 955/4885 |
| US-20090018200-A1 | COMPOSITION CONTAINING A PHENANTHRENOL | CUTA, AHR, TYR | NPSR1 1264/4885EPHX1 556/4885CETP 2043/4885 |
| US-20080160088-A1 | COMPOSITION CONTAINING HYDROXYAPATITE AND A CALCIUM SALT | CA2, NHERF1, CUTA | NPSR1 2644/4885EPHX1 1979/4885CETP 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.