Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.55 |
| ▸ | HTR1D | P28221 | 5/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.51 |
| ▸ | MPO | P05164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11739332 | 0.84 | HTR2A (0.69) | SLC6A4HTR1BMPO | |
| SCHEMBL32669329 | 0.84 | TRPM8 (0.67) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL11739126 | 0.84 | HTR2A (0.60) | SLC6A4MPO | |
| SCHEMBL11737683 | 0.84 | HTR1D (0.48) | HTR6KCNH2TRPM8KDM4EMAPT | |
| SCHEMBL11739008 | 0.82 | MPO (0.57) | HTR6KCNH2SLC6A4MPO | |
| SCHEMBL11471775 | 0.79 | TRPM8 (0.53) | HTR6KCNH2TRPM8KDM4EMAPT | |
| SCHEMBL11735457 | 0.78 | GABRA1 (0.47) | LTA4HPLA2G2APOLB | |
| SCHEMBL11734250 | 0.78 | HTR2A (0.65) | — | |
| SCHEMBL11768689 | 0.77 | DRD3 (0.58) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| Hydrochloric Acid SCHEMBL11767138 | 0.77 | LTA4H (0.59) | TRPM8KDM4EMAPTLTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031221-A | ANALGESICS, TRANQUILIZERS, INDOLE COMPOUNDS | AMERICAN HOECHST CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |