Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 9/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11802836 | 0.76 | GAA (0.57) | GAAMAPTHCAR3VCAM1 | |
| SCHEMBL27899596 | 0.75 | KMT2A (0.45) | GAAVCAM1 | |
| SCHEMBL7826598 | 0.74 | VCAM1 (0.49) | GAAMAPTHCAR3VCAM1TPMT | |
| SCHEMBL135289 | 0.72 | CASP6 (0.47) | GAAMAPTHCAR3VCAM1TPMT | |
| Methylamine SCHEMBL11877019 | 0.71 | TSHR (0.44) | GAAMAPTHCAR3VCAM1TPMT | |
| SCHEMBL31108456 | 0.71 | ALDH1A1 (0.57) | HCAR3VCAM1TPMTTSHR | |
| SCHEMBL573259 | 0.71 | ALDH1A1 (0.57) | HCAR3VCAM1TPMTTSHR | |
| SCHEMBL11847710 | 0.70 | HCAR3 (0.47) | GAAMAPTHCAR3VCAM1TPMT | |
| SCHEMBL573520 | 0.70 | HCAR3 (0.47) | GAAMAPTHCAR3VCAM1TPMT | |
| SCHEMBL30241160 | 0.69 | MAPT (0.44) | GAAMAPTHCAR3VCAM1TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100494172-C | Method of preparing 2-chloro-3-nitro-5-carboxyl benzenesulfonamide | SUZHOU LIXIN PHARMACY CO LTD (CN) | 2009-06-03 | — | — | CN | claimed |
| CN-101033206-A | Method of preparing 2-chloro-3-nitro-5-carboxyl benzenesulfonamide | SUZHOU LIXIN PHARMACY CO LTD (CN) | 2007-09-12 | — | — | CN | claimed |
| CN-100494172-C | Method of preparing 2-chloro-3-nitro-5-carboxyl benzenesulfonamide | SUZHOU LIXIN PHARMACY CO LTD (CN) | 2009-06-03 | — | — | CN | disclosed |
| CN-101033206-A | Method of preparing 2-chloro-3-nitro-5-carboxyl benzenesulfonamide | SUZHOU LIXIN PHARMACY CO LTD (CN) | 2007-09-12 | — | — | CN | disclosed |