SCHEMBL118232

SCHEMBL118232

COc1cc(COC(C)C)ccc1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOS P01100 1/20 0.65
TTR P02766 1/20 0.65
JUN P05412 1/20 0.65
NR3C1 P04150 1/20 0.65
HSD17B1 P14061 1/20 0.65
HSD17B2 P37059 1/20 0.65
ALOX15 P16050 1/20 0.59
ALOX12 P18054 1/20 0.59
PTPN1 P18031 2/20 0.58
TAAR1 Q96RJ0 2/20 0.57
TSHR P16473 2/20 0.57
MAPK1 P28482 1/20 0.57
CYP3A4 P08684 2/20 0.57
MMP1 P03956 1/20 0.57
LMNA P02545 1/20 0.56
GLA P06280 1/20 0.56
ALDH1A1 P00352 2/20 0.54
GAA P10253 1/20 0.54
NFKB1 P19838 1/20 0.54
TDP1 Q9NUW8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31512875 1.00 FOS (0.65) FOSTTRJUNNR3C1HSD17B1
SCHEMBL31512868 0.87 FOS (0.66) FOSTTRJUNNR3C1HSD17B1
SCHEMBL21402282 0.86 ALOX15 (0.65) FOSTTRJUNNR3C1HSD17B1
SCHEMBL31512870 0.85 FOS (0.59) FOSTTRJUNNR3C1HSD17B1
SCHEMBL25586653 0.85 CYP3A4 (0.60) FOSTTRJUNNR3C1HSD17B1
SCHEMBL31512864 0.84 FOS (0.58) FOSTTRJUNNR3C1HSD17B1
SCHEMBL19129605 0.84 CA2 (0.59) ALOX15ALOX12CYP3A4ALDH1A1
SCHEMBL31512862 0.83 FOS (0.57) FOSTTRJUNNR3C1HSD17B1
SCHEMBL3156186 0.83 ALDH1A1 (0.49) FOSTTRJUNNR3C1HSD17B1
SCHEMBL31512872 0.83 FOS (0.56) FOSTTRJUNNR3C1HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4410937-A2 HOUSEHOLD PRODUCT DELIVERING WARMING AND/OR TINGLING SENSATIONS Takasago International Corporation (JP) 2024-08-07 EP claimed
EP-3494104-B1 WARMING SENSATION COMPOUNDS TAKASAGO PERFUMERY CO LTD (JP) 2023-11-15 EP claimed
CN-115721567-A Thermal wet tissue and preparation method thereof 芜湖悠派护理用品科技股份有限公司 2023-03-03 CN claimed
EP-3569671-B1 METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME TAKASAGO PERFUMERY CO LTD (JP) 2022-06-22 EP claimed
US-11344488-B2 Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative TAKASAGO INTERNATIONAL CORPORATION (JP) 2022-05-31 US claimed
CN-110168038-B Methyl menthol derivative and cold sensate composition containing same 高砂香料工业株式会社 2022-05-27 CN claimed
CN-109803948-B Warming sensation compound 高砂香料工业株式会社 2022-03-01 CN claimed
US-11236042-B2 Methylmenthol derivative and cool-sensation imparter composition containing same TAKASAGO INTERNATIONAL CORPORATION (JP) 2022-02-01 US claimed
CN-113389055-A Cool or heat-sensitive microcapsule, nonwoven fabric and absorbent article 上海护理佳实业有限公司 2021-09-14 CN claimed
US-20210236678-A1 HOUSEHOLD PRODUCT DELIVERING WARMING AND/OR TINGLING SENSATIONS TAKASAGO INTERNATIONAL CORPORATION (JP) 2021-08-05 US claimed
EP-0977554-B1 CONFECTIONERY COMPOSITIONS PROCTER & GAMBLE (US) 2004-06-16 EP claimed
EP-0977553-B1 THROAT SOOTHING COMPOSITIONS PROCTER & GAMBLE (US) 2003-09-10 EP claimed
US-6432441-B1 ENCAPSULATION OF ANALGESICS, EXPECTORANTS OR ANTITUSSIVE AGENTS WITHIN PHOSPHATIDES TO PROLONG DRUG DELIVERY THE PROCTER & GAMBLE COMPANY 2002-08-13 US claimed
US-6306429-B1 THROAT DROPS SUITABLE FOR RELIEF OF COUGH AND COLD SYMPTOMS THE PROCTER & GAMBLE COMPANY 2001-10-23 US claimed
EP-0977554-A1 CONFECTIONERY COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-02-09 EP claimed
EP-0977553-A1 THROAT SOOTHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-02-09 EP claimed
WO-1998047483-A1 CONFECTIONERY COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-10-29 WO claimed
WO-1998047482-A1 THROAT SOOTHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-10-29 WO claimed
EP-0837862-A1 WARMING COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1998-04-29 EP claimed
WO-1997002273-A1 WARMING COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1997-01-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11344488-B2 Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative CNR2, ADRB2, TRPA1 FOS 3650/4885TTR 1912/4885JUN 2864/4885
US-11236042-B2 Methylmenthol derivative and cool-sensation imparter composition containing same TRPM8, TRPM4, TRPM2 FOS 3824/4885TTR 3545/4885JUN 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.