Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492547 | 0.85 | PPARG (0.51) | PPARGPPARAHSD17B10 | |
| SCHEMBL7372199 | 0.84 | PPARG (0.50) | ANPEPERAP2ERAP1PPARGPPARA | |
| SCHEMBL3433828 | 0.84 | PPARG (0.50) | ANPEPERAP2ERAP1PPARGPPARA | |
| SCHEMBL11835552 | 0.83 | PPARG (0.47) | PPARGPPARAMMP2KIF11ALDH1A1 | |
| SCHEMBL11827938 | 0.83 | FFAR1 (0.45) | PPARGPPARAALDH1A1 | |
| SCHEMBL11826787 | 0.83 | ALDH1A1 (0.47) | PPARGPPARATSHRALDH1A1HPGD | |
| SCHEMBL11823662 | 0.81 | MMP12 (0.58) | TSHRMMP2MMP9MMP12MMP13 | |
| SCHEMBL11824539 | 0.80 | PPARG (0.49) | PPARGPPARAMMP2MMP9MMP12 | |
| SCHEMBL11823101 | 0.80 | PTGS2 (0.54) | TSHRMME | |
| SCHEMBL11837707 | 0.80 | ALDH1A1 (0.47) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101790512-A | 2 -substituted- 3 -phenylpropionic acid derivatives and their use in the treatment of inflammatory bowel | ALBIREO AB | 2010-07-28 | — | — | CN | disclosed |