Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828893 | 0.89 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10PLK1GAA | |
| SCHEMBL11826787 | 0.89 | ALDH1A1 (0.47) | PPARGPPARAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL11837564 | 0.88 | ALDH1A1 (0.62) | PPARAALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL11827938 | 0.85 | FFAR1 (0.45) | PPARGPPARAL3MBTL1ALDH1A1S1PR1 | |
| SCHEMBL9492547 | 0.83 | PPARG (0.51) | PPARGPPARAHSD17B10 | |
| SCHEMBL27808300 | 0.83 | ANPEP (0.43) | PPARGPPARAALDH1A1HPGDHSD17B10 | |
| SCHEMBL3433828 | 0.82 | PPARG (0.50) | PPARGPPARAHPGD | |
| SCHEMBL7372199 | 0.82 | PPARG (0.50) | PPARGPPARAHPGD | |
| SCHEMBL11837707 | 0.82 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1POLB | |
| SCHEMBL11823101 | 0.82 | PTGS2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |