Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835552 | 0.89 | PPARG (0.47) | ALDH1A1HPGDHSD17B10L3MBTL1S1PR1 | |
| SCHEMBL11828893 | 0.86 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10S1PR1S1PR5 | |
| SCHEMBL11827938 | 0.85 | FFAR1 (0.45) | ALDH1A1TDP1L3MBTL1TAAR1S1PR1 | |
| SCHEMBL11837564 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD17B10S1PR1PPARA | |
| SCHEMBL9492547 | 0.83 | PPARG (0.51) | HSD17B10TAAR1PPARGPPARA | |
| SCHEMBL27808300 | 0.83 | ANPEP (0.43) | ALDH1A1HPGDHSD17B10TSHRPPARG | |
| SCHEMBL7372199 | 0.82 | PPARG (0.50) | HPGDTSHRTDP1PPARGPPARA | |
| SCHEMBL3433828 | 0.82 | PPARG (0.50) | HPGDTSHRTDP1PPARGPPARA | |
| SCHEMBL11823101 | 0.82 | PTGS2 (0.54) | TSHRCYP2C9AKR1C3AKR1C2 | |
| SCHEMBL11837707 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRL3MBTL1CYP2C9AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |