Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12507531 | 0.71 | F10 (0.36) | F10 | |
| SCHEMBL10280029 | 0.70 | CCR1 (0.39) | — | |
| SCHEMBL11959792 | 0.69 | DRD2 (0.34) | — | |
| SCHEMBL12507711 | 0.67 | MAOA (0.33) | F10 | |
| SCHEMBL12101100 | 0.67 | EPHX2 (0.36) | — | |
| SCHEMBL12507710 | 0.67 | STS (0.41) | F10 | |
| SCHEMBL12833317 | 0.66 | SMYD3 (0.32) | — | |
| SCHEMBL764562 | 0.66 | RAB9A (0.47) | — | |
| SCHEMBL12056140 | 0.65 | STS (0.39) | F10 | |
| SCHEMBL3256076 | 0.64 | PDE5A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270557-B1 | ETHYLENEDIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |