Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32669218 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HPGDTDP1LMNAL3MBTL1 | |
| SCHEMBL31275717 | 0.83 | ALDH1A1 (0.42) | ALDH1A1HPGDTDP1LMNAL3MBTL1 | |
| SCHEMBL34472127 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNAL3MBTL1MAPT | |
| SCHEMBL942641 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1LMNAL3MBTL1 | |
| SCHEMBL31143078 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1LMNAL3MBTL1 | |
| SCHEMBL1401678 | 0.79 | SGMS2 (0.46) | ALDH1A1HPGDLMNAMAPTMEN1 | |
| SCHEMBL27538825 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HPGDTDP1LMNAMAPT | |
| SCHEMBL297502 | 0.77 | SMN1; SMN2 (0.43) | ALDH1A1TDP1LMNAL3MBTL1GAA | |
| SCHEMBL10258689 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNAL3MBTL1MAPT | |
| SCHEMBL3028315 | 0.77 | TUBB1 (0.38) | ALDH1A1MAPTTUBB1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034119-A1 | 5-METHOXY-N,N-DIMETHYLTRYPTAMINE ANALOGS, THEIR SYNTHESIS, AND METHODS FOR TREATMENT OF NEUROLOGICAL, PSYCHIATRIC, AND SUBSTANCE USE DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2026-02-05 | — | — | US | disclosed |
| EP-3862354-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2021-08-11 | — | — | EP | disclosed |
| EP-2824105-B1 | Indolopyridines as Eg5 kinesin modulators | 4SC AG (DE) | 2021-03-31 | — | — | EP | disclosed |
| EP-2824105-A1 | Indolopyridines as Eg5 kinesin modulators | 4SC AG (DE) | 2015-01-14 | — | — | EP | disclosed |
| US-8530493-B2 | Indolopyridines as Eg5 kinesin modulators | 4SC AG (DE) | 2013-09-10 | — | — | US | disclosed |
| US-20110027226-A1 | INDOLOPYRIDINES AS INHIBITORS OF THE KINESIN SPINDLE PROTEIN (EG5) | 4SC AG (DE) | 2011-02-03 | — | — | US | disclosed |
| EP-2178875-A1 | INDOLOPYRIDINES AS INHIBITORS OF THE KINESIN SPINDLE PROTEIN (EG5 ) | 4SC AG (DE) | 2010-04-28 | — | — | EP | disclosed |
| US-20090246169-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | NYCOMED GMBH (DE) | 2009-10-01 | — | — | US | disclosed |
| US-20090233902-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2009-09-17 | — | — | US | disclosed |
| EP-2033962-A1 | Tetracyclic indolopyridines as EG5 inhibitors | 4SC AG (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2009024190-A1 | INDOLOPYRIDINES AS INHIBITORS OF THE KINESIN SPINDLE PROTEIN (EG5 ) | 4SC AG (DE) | 2009-02-26 | — | — | WO | disclosed |
| WO-2009024613-A1 | TETRACYCLIC INDOLOPYRIDINES AS EG5 INHIBITORS | 4SC AG (DE) | 2009-02-26 | — | — | WO | disclosed |
| EP-1996592-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | Nycomed GmbH (DE) | 2008-12-03 | — | — | EP | disclosed |
| EP-1994033-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007096393-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007096395-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034119-A1 | 5-METHOXY-N,N-DIMETHYLTRYPTAMINE ANALOGS, THEIR SYNTHESIS, AND METHODS FOR TREATMENT OF NEUROLOGICAL, PSYCHIATRIC, AND SUBSTANCE USE DISORDERS | HTR4, OPRM1, HTR7 | ALDH1A1 858/4885HPGD 1968/4885TDP1 1453/4885 |
| US-20110027226-A1 | INDOLOPYRIDINES AS INHIBITORS OF THE KINESIN SPINDLE PROTEIN (EG5) | KIF5A, KIF5C, KIF5B | ALDH1A1 3349/4885HPGD 4187/4885TDP1 457/4885 |
| US-20090233902-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | KIF5A, KIF5C, KIF5B | ALDH1A1 2483/4885HPGD 3444/4885TDP1 503/4885 |
| US-20090246169-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | KIF5A, KIF5C, KIF5B | ALDH1A1 2483/4885HPGD 3444/4885TDP1 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.