Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17132185 | 0.94 | CA12 (0.39) | CA12CA1CA2CA7CA14 | |
| SCHEMBL13002621 | 0.89 | CYP3A4 (0.45) | CA12CA1CA2CA7CA14 | |
| SCHEMBL16137375 | 0.88 | ALDH1A1 (0.39) | CA12CA1CA2CA7CA14 | |
| SCHEMBL103165 | 0.88 | LMNA (0.43) | CA12CA1CA2CA7CA14 | |
| SCHEMBL13061573 | 0.86 | LMNA (0.46) | CA12CA1CA2CA7CA14 | |
| SCHEMBL17365888 | 0.85 | ALDH1A1 (0.39) | CA12CA1CA2CA7CA14 | |
| SCHEMBL18884176 | 0.85 | CYP3A4 (0.42) | CA12CA1CA2CA7CA14 | |
| SCHEMBL14553993 | 0.84 | CYP3A4 (0.43) | CA12CA1CA2CA7CA14 | |
| SCHEMBL13972410 | 0.81 | LMNA (0.46) | CYP3A4ALDH1A1 | |
| SCHEMBL20253209 | 0.79 | LMNA (0.50) | CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406216-B1 | HALOGENALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | BAYER IP GMBH (DE) | 2017-04-19 | — | — | EP | disclosed |
| EP-3153503-A1 | INTERMEDIATES FOR HALOGENOALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | Bayer Intellectual Property GmbH (DE) | 2017-04-12 | — | — | EP | disclosed |
| US-9272997-B2 | Process for the preparation of 1-H-pyrrolidine-2,4-dione derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9204640-B2 | 2-acyloxy-pyrrolin-4-ones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-9198432-B2 | 1,2,4-triazolyl-substituted ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-9045390-B2 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-9000189-B2 | Biphenyl-substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2015-04-07 | — | — | US | disclosed |
| US-20140371468-A1 | Process for the Preparation of 1-H-pyrrolidine-2,4-dione Derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2014-12-18 | — | — | US | disclosed |
| US-8901038-B2 | Biphenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2014-12-02 | — | — | US | disclosed |
| US-8859782-B2 | Process for the preparation of 1-H-pyrrolidine-2,4-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2014-10-14 | — | — | US | disclosed |
| US-20120190865-A1 | Process for the Preparation of 1-H-pyrrolidine-2,4-dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2012-07-26 | — | — | US | disclosed |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2012-07-12 | — | — | US | disclosed |
| US-20110306499-A1 | Biphenyl-Substituted Spirocyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-12-15 | — | — | US | disclosed |
| US-20110294783-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| US-20110230346-A1 | Biphenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-22 | — | — | US | disclosed |
| US-8013172-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-06 | — | — | US | disclosed |
| US-20100311593-A1 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | BAYER CROPSCIENCE AG (DE) | 2010-12-09 | — | — | US | disclosed |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-12-10 | — | — | US | disclosed |
| US-20090227563-A1 | HERBICIDAL COMPOSITIONS HAVING IMPROVED EFFECT | BAYER CROPSCIENCE AG (DE) | 2009-09-10 | — | — | US | disclosed |
| US-20090209513-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294783-A1 | Insecticidal Compositions Having Improved Effect | FASN, CYP51A1, PIKFYVE | CA12 4429/4885CA1 1784/4885CA2 843/4885 |
| US-20110306499-A1 | Biphenyl-Substituted Spirocyclic Ketoenols | KCNE1, PDHX, PIKFYVE | CA12 1932/4885CA1 853/4885CA2 309/4885 |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | PHYKPL, KCNE1, PIKFYVE | CA12 2153/4885CA1 1054/4885CA2 242/4885 |
| US-20090209513-A1 | Insecticidal Compositions Having Improved Effect | PTEN, PIK3CG, PIK3CD | CA12 3733/4885CA1 1309/4885CA2 469/4885 |
| US-20120190865-A1 | Process for the Preparation of 1-H-pyrrolidine-2,4-dione Derivatives | DHPS, HPD, DOHH | CA12 4201/4885CA1 3506/4885CA2 4067/4885 |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | PHYKPL, KCNE1, PKM | CA12 1749/4885CA1 1167/4885CA2 281/4885 |
| US-20140371468-A1 | Process for the Preparation of 1-H-pyrrolidine-2,4-dione Derivatives | DHPS, HPD, DOHH | CA12 4201/4885CA1 3506/4885CA2 4067/4885 |
| US-20100311593-A1 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | PHYKPL, KCNE1, CSNK1E | CA12 1041/4885CA1 676/4885CA2 81/4885 |
| US-20110230346-A1 | Biphenyl-Substituted Cyclic Ketoenols | KCNE1, KDM4E, PIKFYVE | CA12 2420/4885CA1 1025/4885CA2 134/4885 |
| US-20090227563-A1 | HERBICIDAL COMPOSITIONS HAVING IMPROVED EFFECT | PHYKPL, PPA1, AADAC | CA12 3044/4885CA1 930/4885CA2 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.