SCHEMBL12023973

SCHEMBL12023973

COC(=O)C(C)CC(C)(CC(C)(C)C(=O)O)C(=O)OC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESRRB O95718 1/20 0.32
MMP8 P22894 1/20 0.32
ACACB O00763 1/20 0.32
ACACA Q13085 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17278939 0.82 ACACB (0.37) ESRRBMMP8ACACBACACA
SCHEMBL17897630 0.81 CA2 (0.45) MMP8
SCHEMBL16811778 0.80 MMP8 (0.35) MMP8
SCHEMBL11913584 0.80 MMP8 (0.35) MMP8
SCHEMBL12363480 0.80 MMP8 (0.35) MMP8
SCHEMBL10156018 0.79 MMP8 (0.39) ESRRBMMP8
SCHEMBL10838592 0.78 MMP8 (0.37) ESRRBMMP8
SCHEMBL18098452 0.78 MMP8 (0.37) ESRRBMMP8
SCHEMBL14668148 0.78 DGAT1 (0.34) MMP8
SCHEMBL10349871 0.78 DGAT1 (0.34) MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230346733-A1 ORAL FORMULATIONS OF BIPOLAR TRANS CAROTENOIDS DIFFUSION PHARMACEUTICALS LLC (US) 2023-11-02 US disclosed
US-20230346733-A1 ORAL FORMULATIONS OF BIPOLAR TRANS CAROTENOIDS DIFFUSION PHARMACEUTICALS LLC (US) 2023-11-02 US disclosed
US-20230301923-A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF IMPAX LABORATORIES, LLC (US) 2023-09-28 US disclosed
US-11666538-B2 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof IMPAX LABORATORIES, LLC (US) 2023-06-06 US disclosed
US-11666538-B2 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof IMPAX LABORATORIES, LLC (US) 2023-06-06 US disclosed
US-11622941-B2 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof IMPAX LABORATORIES, LLC (US) 2023-04-11 US disclosed
US-11357733-B2 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof IMPAX LABORATORIES, LLC (US) 2022-06-14 US disclosed
US-20210338591-A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF IMPAX LABORATORIES, LLC (US) 2021-11-04 US disclosed
US-20210205226-A1 ORAL DRUG DOSAGE FORM COMPRISING DRUG IN THE FORM OF NANOPARTICLES Triastek, Inc. (CN) 2021-07-08 US disclosed
US-20210128480-A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF IMPAX LABORATORIES, LLC (US) 2021-05-06 US disclosed
US-20160287523-A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2016-10-06 US disclosed
US-20160287523-A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2016-10-06 US disclosed
US-20160250170-A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2016-09-01 US disclosed
US-20160250170-A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2016-09-01 US disclosed
US-20150352068-A1 ORAL FORMULATIONS OF BIPOLAR TRANS CAROTENOIDS DIFFUSION PHARMACEUTICALS LLC 2015-12-10 US disclosed
US-20150352068-A1 ORAL FORMULATIONS OF BIPOLAR TRANS CAROTENOIDS DIFFUSION PHARMACEUTICALS LLC 2015-12-10 US disclosed
US-8974822-B2 Oral formulations of bipolar trans carotenoids DIFFUSION PHARMACEUTICALS LLC (US) 2015-03-10 US disclosed
US-8974822-B2 Oral formulations of bipolar trans carotenoids DIFFUSION PHARMACEUTICALS LLC (US) 2015-03-10 US disclosed
US-20110300213-A1 Oral formulations of bipolar trans carotenoids DIFFUSION PHARMACEUTICALS LLC 2011-12-08 US disclosed
US-20110300213-A1 Oral formulations of bipolar trans carotenoids DIFFUSION PHARMACEUTICALS LLC 2011-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110300213-A1 Oral formulations of bipolar trans carotenoids CRY1, CYP11B1, BBC3 ESRRB 2754/4885MMP8 4249/4885ACACB 1497/4885
US-20230346733-A1 ORAL FORMULATIONS OF BIPOLAR TRANS CAROTENOIDS CRY1, CYP11B1, BBC3 ESRRB 2754/4885MMP8 4249/4885ACACB 1497/4885
US-20150352068-A1 ORAL FORMULATIONS OF BIPOLAR TRANS CAROTENOIDS CRY1, CYP11B1, BBC3 ESRRB 2754/4885MMP8 4249/4885ACACB 1497/4885
US-11666538-B2 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof COMT, MUC1, MLNR ESRRB 3900/4885MMP8 3922/4885ACACB 2811/4885
US-20160287523-A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF COMT, DDO, SLC6A3 ESRRB 4023/4885MMP8 3664/4885ACACB 1414/4885
US-20160250170-A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF COMT, DDO, DAO ESRRB 3997/4885MMP8 3668/4885ACACB 1344/4885
US-11622941-B2 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof COMT, MUC1, MLNR ESRRB 3900/4885MMP8 3922/4885ACACB 2811/4885
US-20230301923-A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF COMT, MLNR, MUC1 ESRRB 3631/4885MMP8 4423/4885ACACB 2562/4885
US-20210128480-A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF COMT, DDO, SLC6A3 ESRRB 4023/4885MMP8 3664/4885ACACB 1414/4885
US-20210338591-A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF COMT, MUC1, MLNR ESRRB 3900/4885MMP8 3922/4885ACACB 2811/4885
US-11357733-B2 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof COMT, DDO, SLC6A3 ESRRB 4023/4885MMP8 3664/4885ACACB 1414/4885
US-20210205226-A1 ORAL DRUG DOSAGE FORM COMPRISING DRUG IN THE FORM OF NANOPARTICLES CYP2D6, CYP3A5, CYP3A7 ESRRB 4056/4885MMP8 4227/4885ACACB 2326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.