SCHEMBL12048296

SCHEMBL12048296

Cc1ccc(N(C)c2ccc(-c3ccc(N(c4ccccc4)c4cccc5ccccc45)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 8/20 0.43
▸ CHKA P35790 2/20 0.35
▸ PDE5A O76074 2/20 0.35
▸ DHFR P00374 2/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ XBP1 P17861 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ ATM Q13315 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22912468 1.00 SIGMAR1 (0.43) SIGMAR1CHKAPDE5ADHFRNPC1
SCHEMBL12048488 0.97 SIGMAR1 (0.41) SIGMAR1PDE5ADHFRNPC1XBP1
SCHEMBL12048005 0.97 SIGMAR1 (0.41) SIGMAR1PDE5ADHFRNPC1XBP1
SCHEMBL12047792 0.96 SIGMAR1 (0.47) SIGMAR1DHFRL3MBTL1
SCHEMBL12048429 0.94 SIGMAR1 (0.42) SIGMAR1DHFR
SCHEMBL19763114 0.94 SIGMAR1 (0.44) SIGMAR1NPC1XBP1HTTRAB9A
SCHEMBL2607224 0.94 SIGMAR1 (0.44) SIGMAR1NPC1XBP1HTTRAB9A
SCHEMBL12048286 0.94 SIGMAR1 (0.48) SIGMAR1CHKAPDE5ADHFRL3MBTL1
SCHEMBL4570427 0.94 SIGMAR1 (0.44) SIGMAR1NPC1XBP1HTTRAB9A
SCHEMBL16386586 0.94 SIGMAR1 (0.44) SIGMAR1NPC1XBP1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9502662-B2 Compound for an organic optoelectronic device, organic light-emitting element comprising same, and display device comprising the organic light-emitting element CHEIL INDUSTRIES, INC. (KR) 2016-11-22 — — US disclosed
US-9502662-B2 Compound for an organic optoelectronic device, organic light-emitting element comprising same, and display device comprising the organic light-emitting element CHEIL INDUSTRIES, INC. (KR) 2016-11-22 — — US disclosed
US-20150263291-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING ELEMENT CHEIL INDUSTRIES, INC. (KR) 2015-09-17 — — US disclosed
US-20150263291-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING ELEMENT CHEIL INDUSTRIES, INC. (KR) 2015-09-17 — — US disclosed
US-8968884-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2015-03-03 — — US disclosed
US-8968884-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2015-03-03 — — US disclosed
US-8410475-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2013-04-02 — — US disclosed
US-8410475-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2013-04-02 — — US disclosed
US-8071227-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2011-12-06 — — US disclosed
US-8071227-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2011-12-06 — — US disclosed
US-20090200542-A1 Compounds and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-08-13 — — US disclosed
US-20090200542-A1 Compounds and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-08-13 — — US disclosed
US-20090045721-A1 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2009-02-19 — — US disclosed
US-20090045721-A1 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2009-02-19 — — US disclosed
US-20080303434-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2008-12-11 — — US disclosed
US-20080303434-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2008-12-11 — — US disclosed
US-20080093983-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM. LTD. (KR) 2008-04-24 — — US disclosed
US-20080093983-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM. LTD. (KR) 2008-04-24 — — US disclosed
US-20080093982-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2008-04-24 — — US disclosed
US-20080093982-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2008-04-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150263291-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING ELEMENT AOX1, OCIAD1, AOC2 SIGMAR1 1977/4885CHKA 3620/4885PDE5A 3156/4885
US-20090200542-A1 Compounds and Organic Light Emitting Device Using the Same CYBA, LOXL1, OGDH SIGMAR1 3870/4885CHKA 4022/4885PDE5A 3778/4885
US-20080303434-A1 Compound and Organic Light Emitting Device Using the Same PPOX, CRY1, CRY2 SIGMAR1 4092/4885CHKA 4507/4885PDE5A 3095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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