Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL9422173 | 1.00 | TSHR (0.54) | TSHRTHRBLMNAPLA2G1BPLA2G2A | |
| Hexadecane SCHEMBL27942491 | 0.96 | TSHR (0.61) | TSHRTHRBLMNAPLA2G1BPLA2G2A | |
| Heptane SCHEMBL3084197 | 0.96 | TSHR (0.61) | TSHRTHRBLMNAPLA2G1BPLA2G2A | |
| Decane SCHEMBL28273535 | 0.96 | TSHR (0.61) | TSHRTHRBLMNAPLA2G1BPLA2G2A | |
| Tetradecane SCHEMBL28338948 | 0.96 | TSHR (0.61) | TSHRTHRBLMNAPLA2G1BPLA2G2A | |
| SCHEMBL28521976 | 0.96 | TSHR (0.61) | TSHRTHRBLMNAPLA2G1BPLA2G2A | |
| Octane SCHEMBL639987 | 0.96 | TSHR (0.61) | TSHRTHRBLMNAPLA2G1BPLA2G2A | |
| SCHEMBL28338950 | 0.96 | TSHR (0.61) | TSHRTHRBLMNAPLA2G1BPLA2G2A | |
| Nonane SCHEMBL5981632 | 0.93 | TSHR (0.57) | TSHRTHRBLMNAPLA2G1BPLA2G2A | |
| Hexane SCHEMBL27706711 | 0.93 | TSHR (0.47) | TSHRTHRBLMNAPLA2G1BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602053-A | High Charge Density Metal Phosphate Molecular Sieves | 环球油品公司 | 2018-09-28 | — | — | CN | claimed |
| CN-105566348-A | Preparation method of everolimus | HARBIN PHARMACEUTICAL GROUP TECH CENTER | 2016-05-11 | — | — | CN | claimed |
| US-20230365552-A1 | LYSERGIC ACID DERIVATIVES AND METHODS | The Florida State University Research Foundation, Inc. | 2023-11-16 | — | — | US | disclosed |
| WO-2023220381-A1 | LYSERGIC ACID DERIVATIVES AND METHODS | The Florida State University Research Foundation, Inc. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023081141-A1 | THYMIDYLATE SYNTHASE INHIBITORS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-05-11 | — | — | WO | disclosed |
| CN-110343097-B | Asymmetric synthesis method of emtricitabine | 武汉工程大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-114945669-A | Extrahepatic delivery | 阿尔尼拉姆医药品有限公司 | 2022-08-26 | — | — | CN | disclosed |
| US-20220185828-A1 | Silylated Derivatives Of Aromatic Heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2022-06-16 | — | — | US | disclosed |
| US-20220162236-A1 | SILYLATIONS OF AROMATIC SUBSTRATES WITH BASE-ACTIVATED ORGANOSILANES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2022-05-26 | — | — | US | disclosed |
| US-11312733-B2 | Silylated derivatives of aromatic heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2022-04-26 | — | — | US | disclosed |
| US-11242331-B2 | Analogs of yohimbine and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-02-08 | — | — | US | disclosed |
| CN-86105901-A | Agricultural chemical compound | — | 1987-03-11 | — | — | CN | disclosed |
| EP-0094691-B1 | METHOD FOR PREPARING 8-ACYLTHIO-1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3,6(E),11(A)-TRIMETHYL-3-BENZAZOCINES | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1986-08-13 | — | — | EP | disclosed |
| EP-0147217-A2 | Leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1985-07-03 | — | — | EP | disclosed |
| EP-0010896-B1 | ORGANIC DIAMINE COMPOUNDS FOR USE AS ORAL HYPOGLYCEMIC AGENTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER INC. (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4248986-A | COMPRISING AT LEAST TWO DIFFERENT BLOCKS, ONE BLOCK DERIVED FROM A CONJUGATED DIENE MONOMER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-02-03 | — | — | US | disclosed |
| US-4242471-A | CERIVED FROM CONJUGATED DIENE MONOMERS; FOR USE AS COATINGS, ADHESIVES, FILMS, AUTOMOTIVE USES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| US-4212968-A | Prostaglandin derivatives | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4123441-A | Enlarged-hetero-ring prostacyclin analogs | THE UPJOHN COMPANY (US) | 1978-10-31 | — | — | US | disclosed |
| US-4034021-A | Copolymers of pivalolactone and isoprene or butadiene | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11312733-B2 | Silylated derivatives of aromatic heterocycles | KCNH1, KCNH3, HNRNPH3 | TSHR 4729/4885THRB 4709/4885LMNA 975/4885 |
| US-20220162236-A1 | SILYLATIONS OF AROMATIC SUBSTRATES WITH BASE-ACTIVATED ORGANOSILANES | TYR, DDC, TPST2 | TSHR 4704/4885THRB 4703/4885LMNA 1864/4885 |
| US-11242331-B2 | Analogs of yohimbine and uses thereof | MAOA, MAOB, NPY5R | TSHR 529/4885THRB 590/4885LMNA 543/4885 |
| US-20220185828-A1 | Silylated Derivatives Of Aromatic Heterocycles | KCNH1, KCNH3, HNRNPH3 | TSHR 4729/4885THRB 4709/4885LMNA 975/4885 |
| US-20230365552-A1 | LYSERGIC ACID DERIVATIVES AND METHODS | AADAT, HTR3A, HNMT | TSHR 1456/4885THRB 1051/4885LMNA 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.