Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 2/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | RARG | P13631 | 2/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14146468 | 0.90 | PGR (0.40) | PGRDHODHCXCR3KMT2A | |
| SCHEMBL14668959 | 0.90 | CCR2 (0.32) | PGRRARARARBRARGCXCR3 | |
| SCHEMBL13821952 | 0.78 | — | — | |
| SCHEMBL7077762 | 0.78 | — | — | |
| SCHEMBL14146797 | 0.78 | ALDH1A1 (0.33) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL14146475 | 0.75 | PGR (0.38) | PGR | |
| SCHEMBL14146465 | 0.75 | GABRA1 (0.35) | — | |
| SCHEMBL14146469 | 0.73 | KMO (0.39) | PGR | |
| SCHEMBL14146749 | 0.72 | GABRG2 (0.36) | PGRMEN1KMT2A | |
| SCHEMBL14146464 | 0.71 | CYP11B1 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130026909-A1 | HOST MATERIALS FOR PHOSPHORESCENT OLEDS | UNIVERSAL DISPLAY CORPORATION (US) | 2013-01-31 | — | — | US | disclosed |
| US-20120298966-A1 | Host materials for oled | UNIVERSAL DISPLAY CORPORATION (US) | 2012-11-29 | — | — | US | disclosed |
| US-8062768-B2 | Compound comprising phenyl pyridine units | GENERAL ELECTRIC COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| US-8053095-B2 | Compound comprising phenyl pyridine units | GENERAL ELECTRIC COMPANY (US) | 2011-11-08 | — | — | US | disclosed |
| US-20110121235-A1 | COMPOUND COMPRISING PHENYL PYRIDINE UNITS | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120298966-A1 | Host materials for oled | OCIAD2, OCIAD1, OSBP2 | PGR 1515/4885DHODH 1367/4885PTPN5 3736/4885 |
| US-20130026909-A1 | HOST MATERIALS FOR PHOSPHORESCENT OLEDS | OSBP2, OCIAD2, OCIAD1 | PGR 1196/4885DHODH 1367/4885PTPN5 3181/4885 |
| US-20110121235-A1 | COMPOUND COMPRISING PHENYL PYRIDINE UNITS | CRY1, C1S, C3AR1 | PGR 785/4885DHODH 3889/4885PTPN5 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.