Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411709 | 0.82 | POLB (0.33) | IDO1AKR1B1CHRNB4CHRNA3MAPT | |
| SCHEMBL811745 | 0.82 | IDO1 (0.44) | IDO1PTGS2MAPTHTTSMN1; SMN2 | |
| SCHEMBL12658317 | 0.82 | LMNA (0.41) | LMNAIDO1PTGS2 | |
| SCHEMBL148110 | 0.82 | IDO1 (0.46) | LMNAIDO1PTGS2 | |
| SCHEMBL1437868 | 0.82 | PTGS2 (0.39) | IDO1PTGS2MAPTHTTSMN1; SMN2 | |
| SCHEMBL29472374 | 0.78 | IDO1 (0.34) | IDO1AKR1B1CHRNB4CHRNA3MAOB | |
| SCHEMBL671058 | 0.78 | IDO1 (0.34) | IDO1AKR1B1CHRNB4CHRNA3MAOB | |
| SCHEMBL31716590 | 0.78 | IDO1 (0.34) | IDO1AKR1B1CHRNB4CHRNA3MAOB | |
| SCHEMBL16679916 | 0.78 | IDO1 (0.34) | IDO1AKR1B1CHRNB4CHRNA3MAOB | |
| Nitrogen SCHEMBL27562848 | 0.77 | PTGS2 (0.36) | IDO1PTGS2MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| US-11661397-B2 | 1,4-disubstituted imidazole derivative | Sumitomo Pharma Co., Ltd. (JP) | 2023-05-30 | — | — | US | disclosed |
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |
| US-20210171440-A1 | 1,4-DISUBSTITUTED IMIDAZOLE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2021-06-10 | — | — | US | disclosed |
| US-20210015885-A1 | SMALL MOLECULE RAS INHIBITORS | OHIO STATE INNOVATION FOUNDATION | 2021-01-21 | — | — | US | disclosed |
| US-10807945-B2 | 1,4-disubstituted imidazole derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-10-20 | — | — | US | disclosed |
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |
| EP-3063143-B1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | disclosed |
| EP-3312170-A1 | 1,4-DI-SUBSTITUTED IMIDAZOLE DERIVATIVE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2018-04-25 | — | — | EP | disclosed |
| CN-105209444-B | It can be used as the benzo-fused heterocycle derivative of GPR120 activator | 詹森药业有限公司 | 2017-12-29 | — | — | CN | disclosed |
| US-8884029-B2 | Dye for photoelectric conversion device and photoelectric conversion device | ADEKA CORPORATION (JP) | 2014-11-11 | — | — | US | disclosed |
| EP-2330680-B1 | DYE FOR PHOTOELECTRIC CONVERSION ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT | TDK CORP (JP) | 2013-10-23 | — | — | EP | disclosed |
| CN-103030646-A | Benzodioxane derivative, and preparation method thereof and application of derivative in medicines | SHANGHAI HENGRUI PHARM CO LTD | 2013-04-10 | — | — | CN | disclosed |
| US-8367679-B2 | Biaryl carboxamides | MERCK SHARP & DOHME CORP. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20110253218-A1 | DYE FOR PHOTOELECTRIC CONVERSION DEVICE AND PHOTOELECTRIC CONVERSION DEVICE | ADEKA CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| US-20110253218-A1 | DYE FOR PHOTOELECTRIC CONVERSION DEVICE AND PHOTOELECTRIC CONVERSION DEVICE | ADEKA CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| EP-2372829-A1 | PIGMENT FOR USE WITH PHOTOELECTRIC CONVERSION ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT | TDK Corporation (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-20110230498-A1 | BIARYL CARBOXAMIDES | MERCK SHARP & DOHME CORP. | 2011-09-22 | — | — | US | disclosed |
| US-20110155249-A1 | DYE FOR PHOTOELECTRIC CONVERSION DEVICE AND PHOTOELECTRIC CONVERSION DEVICE | TDK CORPORATION (JP) | 2011-06-30 | — | — | US | disclosed |
| US-20110155249-A1 | DYE FOR PHOTOELECTRIC CONVERSION DEVICE AND PHOTOELECTRIC CONVERSION DEVICE | TDK CORPORATION (JP) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110155249-A1 | DYE FOR PHOTOELECTRIC CONVERSION DEVICE AND PHOTOELECTRIC CONVERSION DEVICE | INMT, HCN2, HCN1 | LMNA 1012/4885IDO1 11/4885PTGS2 3126/4885 |
| US-20110230498-A1 | BIARYL CARBOXAMIDES | PAFAH1B3, PAFAH1B2, FAAH2 | LMNA 1295/4885IDO1 1161/4885PTGS2 221/4885 |
| US-20210171440-A1 | 1,4-DISUBSTITUTED IMIDAZOLE DERIVATIVE | NR4A3, NR0B1, NR2C2 | LMNA 3967/4885IDO1 847/4885PTGS2 1790/4885 |
| US-11661397-B2 | 1,4-disubstituted imidazole derivative | NR4A3, NR0B1, NR2C2 | LMNA 3967/4885IDO1 847/4885PTGS2 1790/4885 |
| US-20210015885-A1 | SMALL MOLECULE RAS INHIBITORS | KRAS, HRAS, NRAS | LMNA 3756/4885IDO1 4601/4885PTGS2 2677/4885 |
| US-10807945-B2 | 1,4-disubstituted imidazole derivative | NR0B1, NR4A3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | LMNA 4055/4885IDO1 841/4885PTGS2 2234/4885 |
| US-20110253218-A1 | DYE FOR PHOTOELECTRIC CONVERSION DEVICE AND PHOTOELECTRIC CONVERSION DEVICE | HCN1, HCN2, HCN3 | LMNA 539/4885IDO1 20/4885PTGS2 3358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.