Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29785212 | 1.00 | ALDH1A1 (0.32) | ALDH1A1MAPTDRD1ACHE | |
| SCHEMBL18788587 | 0.87 | DRD1 (0.33) | DRD1 | |
| SCHEMBL31084185 | 0.87 | POLB (0.33) | ALDH1A1MAPT | |
| SCHEMBL31648729 | 0.85 | — | — | |
| SCHEMBL17747369 | 0.84 | — | — | |
| SCHEMBL20478038 | 0.83 | — | — | |
| SCHEMBL29269 | 0.81 | DRD1 (0.42) | DRD1 | |
| SCHEMBL29663718 | 0.81 | DRD1 (0.42) | DRD1 | |
| SCHEMBL17747367 | 0.81 | — | — | |
| SCHEMBL17747359 | 0.80 | DRD2 (0.36) | DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11591314-B2 | Process for preparing tetrahydrocarbazole carboxamide compound | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-02-28 | — | — | US | claimed |
| US-20210078980-A1 | PROCESS FOR PREPARING TETRAHYDROCARBAZOLE CARBOXAMIDE COMPOUND | BRISTOL MYERS SQUIBB CO (US) | 2021-03-18 | — | — | US | claimed |
| US-10875843-B2 | Process for preparing tetrahydrocarbazole carboxamide compound | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-12-29 | — | — | US | claimed |
| EP-3558977-B1 | PROCESS FOR PREPARING TETRAHYDROCARBAZOLE CARBOXAMIDE COMPOUND | BRISTOL MYERS SQUIBB CO (US) | 2020-10-28 | — | — | EP | claimed |
| US-20200109133-A1 | PROCESS FOR PREPARING TETRAHYDROCARBAZOLE CARBOXAMIDE COMPOUND | BRISTOL MYERS SQUIBB CO (US) | 2020-04-09 | — | — | US | claimed |
| US-11591314-B2 | Process for preparing tetrahydrocarbazole carboxamide compound | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-02-28 | — | — | US | disclosed |
| US-20210078980-A1 | PROCESS FOR PREPARING TETRAHYDROCARBAZOLE CARBOXAMIDE COMPOUND | BRISTOL MYERS SQUIBB CO (US) | 2021-03-18 | — | — | US | disclosed |
| US-10875843-B2 | Process for preparing tetrahydrocarbazole carboxamide compound | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-12-29 | — | — | US | disclosed |
| EP-3558977-B1 | PROCESS FOR PREPARING TETRAHYDROCARBAZOLE CARBOXAMIDE COMPOUND | BRISTOL MYERS SQUIBB CO (US) | 2020-10-28 | — | — | EP | disclosed |
| US-20200109133-A1 | PROCESS FOR PREPARING TETRAHYDROCARBAZOLE CARBOXAMIDE COMPOUND | BRISTOL MYERS SQUIBB CO (US) | 2020-04-09 | — | — | US | disclosed |
| US-10273213-B2 | Method for the production of praziquantel and precursors thereof | MERCK PATENT GMBH (DE) | 2019-04-30 | — | — | US | disclosed |
| US-9896402-B2 | Method for preventing decrease in optical purity | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2018-02-20 | — | — | US | disclosed |
| EP-2774908-A1 | METHOD FOR PREVENTING DECREASE IN OPTICAL PURITY | Takasago International Corporation (JP) | 2014-09-10 | — | — | EP | disclosed |
| US-20140187809-A1 | NOVEL RUTHENIUM COMPLEX AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL COMPOUND USING SAME AS CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-07-03 | — | — | US | disclosed |
| EP-2695887-A1 | NOVEL RUTHENIUM COMPLEX AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL COMPOUND USING SAME AS CATALYST | Takasago International Corporation (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-20130041151-A1 | RUTHENIUM COMPLEX AND METHOD FOR PREPARING OPTICALLY ACTIVE ALCOHOL COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-02-14 | — | — | US | disclosed |
| US-8293938-B2 | Alkylphosphonous acids, salts and esters, methods for the production thereof, and use of the same | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-10-23 | — | — | US | disclosed |
| US-8207379-B2 | Ruthenium compound and method for producing optically active aminoalcohol compound | NIPPON SODA CO., LTD. (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20110028749-A1 | RUTHENIUM COMPOUND AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINOALCOHOL COMPOUND | NIPPON SODA CO., LTD. (JP) | 2011-02-03 | — | — | US | disclosed |
| US-20100190901-A1 | Alkylphosphonous Acids, Salts and Esters, Methods for the Production Thereof, and Use of the Same | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210078980-A1 | PROCESS FOR PREPARING TETRAHYDROCARBAZOLE CARBOXAMIDE COMPOUND | CYP2C8, CYP3A7, PARP8 | ALDH1A1 1428/4885MAPT 2849/4885DRD1 1140/4885 |
| US-11591314-B2 | Process for preparing tetrahydrocarbazole carboxamide compound | CYP2C8, CYP3A7, PARP8 | ALDH1A1 1428/4885MAPT 2849/4885DRD1 1140/4885 |
| US-20130041151-A1 | RUTHENIUM COMPLEX AND METHOD FOR PREPARING OPTICALLY ACTIVE ALCOHOL COMPOUND | ADH5, ADH1C, ADH1A | ALDH1A1 29/4885MAPT 3956/4885DRD1 121/4885 |
| US-10875843-B2 | Process for preparing tetrahydrocarbazole carboxamide compound | CYP2C8, CYP3A7, CDK8 | ALDH1A1 1492/4885MAPT 2690/4885DRD1 1403/4885 |
| US-10273213-B2 | Method for the production of praziquantel and precursors thereof | CYP51A1, POR, DHPS | ALDH1A1 519/4885MAPT 4835/4885DRD1 2474/4885 |
| US-20140187809-A1 | NOVEL RUTHENIUM COMPLEX AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL COMPOUND USING SAME AS CATALYST | ADH1C, ADH5, ADH1A | ALDH1A1 24/4885MAPT 3648/4885DRD1 117/4885 |
| US-20200109133-A1 | PROCESS FOR PREPARING TETRAHYDROCARBAZOLE CARBOXAMIDE COMPOUND | CYP2C8, CYP3A7, CDK8 | ALDH1A1 1492/4885MAPT 2690/4885DRD1 1403/4885 |
| US-20110028749-A1 | RUTHENIUM COMPOUND AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINOALCOHOL COMPOUND | PDHX, PKLR, RIOX2 | ALDH1A1 715/4885MAPT 4345/4885DRD1 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.