SCHEMBL12292385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23746831	1.00	ALDH1A1 (0.33)	ALDH1A1TSHRHSD17B10CYP2D6CYP2C9
	SCHEMBL16704406	0.90	ACHE (0.33)	CYP2D6
	SCHEMBL29555023	0.89	CYP2C9 (0.33)	CYP2C9
	SCHEMBL12856477	0.89	TSHR (0.34)	TSHR
	SCHEMBL10066719	0.89	CYP2C9 (0.33)	CYP2C9
	SCHEMBL13948908	0.88	TSHR (0.33)	TSHR
	SCHEMBL12575575	0.87	CRHR1 (0.32)	—
	SCHEMBL13321310	0.85	KIF11 (0.38)	TSHR
	SCHEMBL12856567	0.84	ALDH1A1 (0.35)	ALDH1A1TSHRHSD17B10CYP2D6CYP2C9
	SCHEMBL12856442	0.84	MEN1 (0.36)	ALDH1A1TSHRCYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.