Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.82 |
| ▸ | MEN1 | O00255 | 5/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.79 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337860 | 0.76 | HTT (0.70) | KMT2AMEN1ALDH1A1HTTKDM4E | |
| SCHEMBL9817959 | 0.73 | CYP1A2 (0.63) | KMT2AMEN1ALDH1A1HTTKDM4E | |
| SCHEMBL13953865 | 0.70 | KMT2A (0.69) | KMT2AMEN1ALDH1A1HTTKDM4E | |
| SCHEMBL11529594 | 0.70 | HTT (0.61) | KMT2AMEN1ALDH1A1HTTKDM4E | |
| SCHEMBL11406171 | 0.70 | ADRB2 (0.66) | KMT2AMEN1ALDH1A1HTTKDM4E | |
| Oxalic Acid SCHEMBL9336253 | 0.70 | SMN1; SMN2 (0.56) | KMT2AMEN1ALDH1A1HTTKDM4E | |
| Oxalic Acid SCHEMBL9336263 | 0.70 | SMN1; SMN2 (0.56) | KMT2AMEN1ALDH1A1HTTKDM4E | |
| SCHEMBL9339905 | 0.69 | HTT (0.60) | KMT2AMEN1ALDH1A1HTTKDM4E | |
| SCHEMBL9339910 | 0.69 | HTT (0.60) | KMT2AMEN1ALDH1A1HTTKDM4E | |
| SCHEMBL17244724 | 0.69 | ALDH1A1 (1.00) | KMT2AMEN1ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263642-B2 | Antimicrobial compounds and methods of use thereof | VANDERBILT UNIVERSITY (US) | 2012-09-11 | — | — | US | disclosed |
| US-8263642-B2 | Antimicrobial compounds and methods of use thereof | VANDERBILT UNIVERSITY (US) | 2012-09-11 | — | — | US | disclosed |
| US-20100004324-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF USE THEREOF | VANDERBILT UNIVERSITY | 2010-01-07 | — | — | US | disclosed |
| US-20100004324-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF USE THEREOF | VANDERBILT UNIVERSITY | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004324-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF USE THEREOF | HMOX1, HMOX2, NOD2 | KMT2A 4544/4885MEN1 4247/4885ALDH1A1 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.