Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 5/20 | 0.52 |
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.52 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.52 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.52 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28135562 | 0.81 | S100A4 (0.35) | CDC25BMAOAMAOBALOX15MEN1 | |
| SCHEMBL7602072 | 0.77 | KMT2A (0.35) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| Triphenylene SCHEMBL5429154 | 0.76 | KDM4E (0.30) | MAOAKDM4EALDH1A1MAPTHPGD | |
| Naphthoquinone SCHEMBL27677906 | 0.76 | CDC25B (0.67) | CDC25BIDO1PIN1MAOAMAOB | |
| Naphthalene SCHEMBL27561595 | 0.76 | CYP2A6 (0.38) | — | |
| Biphenyl SCHEMBL27460490 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TDP1TP53CYP3A4 | |
| Benzoquinone SCHEMBL27507434 | 0.74 | ALDH1A1 (0.36) | MAOAMAOBALDH1A1RECQLHSD17B10 | |
| SCHEMBL6771389 | 0.73 | NISCH (0.37) | MAOAMAOBALOX15KDM4EALDH1A1 | |
| SCHEMBL28530787 | 0.72 | ALOX15 (0.43) | ALOX15MEN1KMT2AALDH1A1MAPT | |
| Benzene SCHEMBL27406391 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410173-B | Pyran naphthoquinone compound, preparation method, composition and application thereof | 兰州大学 | 2024-06-11 | — | — | CN | claimed |
| CN-117567424-A | Method for preparing sulfur-containing pyran naphthoquinone compound by co-culture of streptomycete-bacillus and application of sulfur-containing pyran naphthoquinone compound | 南京中医药大学 | 2024-02-20 | — | — | CN | claimed |
| CN-116410173-A | Pyran naphthoquinone compound, preparation method, composition and application thereof | 兰州大学 | 2023-07-11 | — | — | CN | claimed |
| US-20180055816-A1 | PYRANONAPHTHOQUINONE COMPOUNDS AND METHODS OF USE THEREOF | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-03-01 | — | — | US | claimed |
| JP-63277680-A | — | — | None | — | — | JP | disclosed |
| US-12037342-B2 | Substituted eneoxindoles and uses thereof | GILEAD SCIENCES, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| CN-118355020-A | Therapeutic compounds for HIV virus infection | 吉利德科学公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| US-20240226130-A1 | 4'-THIONUCLEOSIDE ANALOGUES AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES, INC. | 2024-07-11 | — | — | US | disclosed |
| EP-4310087-B1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2024-07-03 | — | — | EP | disclosed |
| US-12024528-B2 | Bridged tricyclic carbamoylpyridone compounds and uses thereof | GILEAD SCIENCES, INC. (US) | 2024-07-02 | — | — | US | disclosed |
| WO-2024137852-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| EP-2137168-A1 | NOVEL IDO INHIBITORS AND METHODS OF USE THEREOF | Lankenau Institute for Medical Research (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008115804-A1 | NOVEL IDO INHIBITORS AND METHODS OF USE THEREOF | LANKENAU INSTITUTE FOR MEDICAL RESEARCH (US) | 2008-09-25 | — | — | WO | disclosed |
| EP-1650209-A1 | Griseusin derivatives and their use as antitumor agents | Oncotest GmbH (DE) | 2006-04-26 | — | — | EP | disclosed |
| US-5736523-A | ADMINISTERING TO THE MAMMAL SUFFERING FROM CANCER | BIOCHEM PHARMA INC. (CA) | 1998-04-07 | — | — | US | disclosed |
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | disclosed |
| EP-0659190-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC (CA) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994011382-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC. (CA) | 1994-05-26 | — | — | WO | disclosed |
| JP-S63277680-A | PORPHYRIN COMPOUND, ITS PRODUCTION AND FLUORESCENT COLOR-DEVELOPING AGENT CONTAINING SAID COMPOUND | NIPPON OIL & FATS CO LTD | 1988-11-15 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226130-A1 | 4'-THIONUCLEOSIDE ANALOGUES AND THEIR PHARMACEUTICAL USE | TYMP, MTAP, TPMT | CDC25B 2392/4885IDO1 2551/4885PIN1 2343/4885 |
| US-12037342-B2 | Substituted eneoxindoles and uses thereof | HIPK1, HPGDS, HIPK3 | CDC25B 1388/4885IDO1 329/4885PIN1 1769/4885 |
| US-12024528-B2 | Bridged tricyclic carbamoylpyridone compounds and uses thereof | SDHA, SDHB, DPYD | CDC25B 727/4885IDO1 1734/4885PIN1 998/4885 |
| US-20180055816-A1 | PYRANONAPHTHOQUINONE COMPOUNDS AND METHODS OF USE THEREOF | EIF4EBP1, EIF4E, MTOR | CDC25B 495/4885IDO1 4639/4885PIN1 1555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.