Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366179 | 0.86 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL12366170 | 0.80 | CNR1 (0.46) | P2RX7 | |
| SCHEMBL12366137 | 0.80 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL12366133 | 0.79 | HPGD (0.54) | — | |
| SCHEMBL12261238 | 0.79 | BDKRB1 (0.40) | P2RX7 | |
| SCHEMBL12366210 | 0.78 | ERCC1 (0.40) | P2RX7 | |
| SCHEMBL12366161 | 0.77 | RIPK1 (0.38) | P2RX7 | |
| SCHEMBL28170737 | 0.76 | P2RX7 (0.53) | P2RX7CA2 | |
| SCHEMBL2263310 | 0.75 | MCL1 (0.51) | P2RX7CA2 | |
| SCHEMBL12366168 | 0.75 | P2RX7 (0.44) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |