Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366137 | 0.88 | P2RX7 (0.50) | MAPK8ERCC1ERCC4RAB9AP2RX7 | |
| SCHEMBL12366210 | 0.83 | ERCC1 (0.40) | ALDH1A1MAPTERCC1ERCC4RAB9A | |
| SCHEMBL12366161 | 0.82 | RIPK1 (0.38) | P2RX7ROCK2ROCK1CHRM4 | |
| SCHEMBL12366133 | 0.81 | HPGD (0.54) | ALDH1A1LMNAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL12366166 | 0.80 | P2RX7 (0.49) | P2RX7 | |
| SCHEMBL4033108 | 0.80 | CNR1 (0.52) | CNR1ALDH1A1LMNAMAPTMAPK8 | |
| SCHEMBL12366135 | 0.78 | LMNA (0.62) | ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL3562274 | 0.77 | ALDH1A1 (0.48) | CNR1ALDH1A1LMNAMAPTMAPK8 | |
| SCHEMBL14393385 | 0.77 | LMNA (0.52) | CNR1ALDH1A1LMNAMAPT | |
| SCHEMBL12366168 | 0.77 | P2RX7 (0.44) | ALDH1A1LMNAP2RX7TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |