Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 13/20 | 0.43 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12368141 | 0.69 | TYMS (0.46) | TYMSXDHDHFRPABPC1 | |
| SCHEMBL2003431 | 0.61 | TYMS (0.76) | TYMS | |
| SCHEMBL6649272 | 0.60 | TYMS (1.00) | TYMS | |
| SCHEMBL576094 | 0.59 | ACHE (0.53) | — | |
| SCHEMBL4313736 | 0.59 | PARP1 (0.70) | TYMSQTRT1 | |
| SCHEMBL6648263 | 0.58 | TYMS (1.00) | TYMS | |
| SCHEMBL12620146 | 0.58 | TYMS (0.60) | TYMS | |
| SCHEMBL28413615 | 0.58 | ATAD2 (0.48) | — | |
| SCHEMBL15906499 | 0.57 | HTR1A (0.50) | — | |
| Hydrogen Sulfide SCHEMBL11580912 | 0.57 | HTR1A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207753-A1 | METHODS FOR TREATING PAIN | THE GENERAL HOSPITAL CORPORATION (US) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207753-A1 | METHODS FOR TREATING PAIN | SPR, QDPR, SHMT1 | TYMS 722/4885QTRT1 64/4885XDH 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.