SCHEMBL12371192

SCHEMBL12371192

CC(C)(C)NCCOCCOCCO

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
TSHR P16473 2/20 0.46
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 5/20 0.41
THRB P10828 1/20 0.40
HTT P42858 1/20 0.40
MAPT P10636 1/20 0.40
GAA P10253 1/20 0.33
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18889881 1.00 MEN1 (0.50) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL18611603 1.00 MEN1 (0.50) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL22932137 1.00 MEN1 (0.50) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL246192 0.98 TSHR (0.48) MEN1KMT2ATSHRMAPK1ALDH1A1
Ammonia Solution, Strong SCHEMBL21800787 0.95 TSHR (0.46) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL22932140 0.94 MEN1 (0.45) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL18611911 0.94 MEN1 (0.50) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL9541679 0.88 KDM4E (0.45) MEN1KMT2AALDH1A1KDM4EGAA
SCHEMBL9540608 0.88 KDM4E (0.45) MEN1KMT2AALDH1A1KDM4EGAA
SCHEMBL14198320 0.88 KDM4E (0.45) MEN1KMT2AALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180257022-A1 ABSORPTION AGENT AND A METHOD FOR SELECTIVELY REMOVING HYDROGEN SULPHIDE BASF SE (DE) 2018-09-13 US claimed
EP-3356014-A1 ABSORPTION AGENT AND A METHOD FOR SELECTIVELY REMOVING HYDROGEN SULPHIDE BASF SE (DE) 2018-08-08 EP claimed
US-20140255250-A1 INHIBITION OF CORROSION IN BOILER SYSTEMS WITH ETHERAMINES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-09-11 US claimed
US-8771594-B2 Inhibition of corrosion in boiler systems with etheramines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-07-08 US claimed
WO-2013173423-A1 AMINE GAS TREATMENT SOLUTIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-11-21 WO claimed
US-20130309129-A1 INHIBITION OF CORROSION IN BOILER SYSTEMS WITH ETHERAMINES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-11-21 US claimed
US-20130310623-A1 AMINE GAS TREATMENT SOLUTIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-11-21 US claimed
US-12138583-B2 Process for removal of acid gases from a fluid stream with a liquid absorbent comprising a piperazine ring BASF SE (DE) 2024-11-12 US disclosed
US-20230357180-A1 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2023-11-09 US disclosed
US-11806404-B2 Site specific homogeneous with KSP inhibitors BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2023-11-07 US disclosed
EP-3927450-B1 PROCESS FOR REMOVAL OF ACID GASES FROM A FLUID STREAM WITH A LIQUID ABSORBENT COMPRISING A PIPERAZINE RING BASF SE (DE) 2023-06-07 EP disclosed
US-11584748-B2 Spirocyclic compounds C4 THERAPEUTICS, INC. (US) 2023-02-21 US disclosed
US-20230019060-A1 HETEROCYCLIC COMPOUNDS FOR MEDICAL TREATMENT C4 THERAPEUTICS, INC. (US) 2023-01-19 US disclosed
WO-2013173423-A1 AMINE GAS TREATMENT SOLUTIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-11-21 WO disclosed
US-20130310623-A1 AMINE GAS TREATMENT SOLUTIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-11-21 US disclosed
US-20130240047-A1 LOW TEMPERATURE TRANSPORT AND STORAGE OF AMINE GAS TREATMENT SOLUTIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-09-19 US disclosed
US-20130142717-A1 OFFSHORE GAS SEPARATION PROCESS SISKIN MICHAEL (US) 2013-06-06 US disclosed
WO-2013082242-A1 OFFSHORE GAS SEPARATION PROCESS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-06-06 WO disclosed
US-20110202328-A1 System for the determination of selective absorbent molecules through predictive correlations EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-08-18 US disclosed
US-20110202328-A1 System for the determination of selective absorbent molecules through predictive correlations EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11806404-B2 Site specific homogeneous with KSP inhibitors KIF5B, KIF15, KIF2C MEN1 1809/4885KMT2A 588/4885TSHR 4784/4885
US-20230019060-A1 HETEROCYCLIC COMPOUNDS FOR MEDICAL TREATMENT CRBN, MDM2, RBX1 MEN1 1285/4885KMT2A 1310/4885TSHR 3515/4885
US-20130310623-A1 AMINE GAS TREATMENT SOLUTIONS GPX4, OAT, HNMT MEN1 3493/4885KMT2A 2802/4885TSHR 3422/4885
US-20230357180-A1 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION STUB1, MDM2, USP30 MEN1 1550/4885KMT2A 2363/4885TSHR 1595/4885
US-11584748-B2 Spirocyclic compounds CRBN, RBX1, XIAP MEN1 1561/4885KMT2A 1849/4885TSHR 3397/4885
US-12138583-B2 Process for removal of acid gases from a fluid stream with a liquid absorbent comprising a piperazine ring AVPR2, HRH2, SLC43A1 MEN1 2204/4885KMT2A 3480/4885TSHR 1330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.