Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.39 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695311 | 1.00 | DNM1 (0.55) | DNM1LPAR1LPAR3LPAR2ALDH1A1 | |
| SCHEMBL1236524 | 1.00 | DNM1 (0.55) | DNM1LPAR1LPAR3LPAR2ALDH1A1 | |
| SCHEMBL13725568 | 1.00 | DNM1 (0.55) | DNM1LPAR1LPAR3LPAR2ALDH1A1 | |
| SCHEMBL1904370 | 0.98 | DNM1 (0.52) | DNM1LPAR1LPAR3LPAR2ALDH1A1 | |
| SCHEMBL4488279 | 0.91 | DNM1 (0.43) | DNM1LPAR1LPAR3LPAR2ALDH1A1 | |
| SCHEMBL27662706 | 0.86 | DNM1 (0.64) | DNM1LPAR1LPAR3LPAR2ALDH1A1 | |
| SCHEMBL28019342 | 0.85 | DNM1 (0.53) | DNM1LPAR1LPAR3LPAR2ALDH1A1 | |
| SCHEMBL6050344 | 0.85 | DNM1 (0.53) | DNM1LPAR1LPAR3LPAR2ALDH1A1 | |
| SCHEMBL1904373 | 0.84 | DNM1 (0.60) | DNM1LPAR1LPAR3LPAR2ALDH1A1 | |
| SCHEMBL27882996 | 0.83 | DNM1 (0.38) | DNM1LPAR1LPAR3LPAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6726915-B2 | DIAMIDE COMPOUNDS RETAINING GOOD COSMETIC PROPERTIES, IN PARTICULAR A CERTAIN LEVEL OF | L'OREAL (FR) | 2004-04-27 | — | — | US | claimed |
| US-20030129211-A9 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | L'OREAL S.A. (FR) | 2003-07-10 | — | — | US | claimed |
| US-20020150602-A1 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | LIVOREIL AUDE (FR) | 2002-10-17 | — | — | US | claimed |
| WO-2012150866-A1 | PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF | INDUSTRIAL RESEARCH LIMITED (NZ) | 2012-11-08 | — | — | WO | disclosed |
| EP-1676556-B1 | Cosmetic composition containing a polyorganosiloxane polymer | OREAL (FR) | 2012-01-11 | — | — | EP | disclosed |
| US-20110189117-A1 | COSMETIC COMPOSITION CONTAINING A POLYORGANISILOXANE POLYMER | L'OREAL (FR) | 2011-08-04 | — | — | US | disclosed |
| US-7879316-B2 | Mixture of polyamide-siloxane copolymer in volatile oil; cosmetics | L'OREAL (FR) | 2011-02-01 | — | — | US | disclosed |
| US-7820146-B2 | Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form | L'OREAL S.A. (FR) | 2010-10-26 | — | — | US | disclosed |
| US-7803356-B2 | Compositions containing at least one silicone resin and a volatile non-cyclic silicone oil | L'OREAL (FR) | 2010-09-28 | — | — | US | disclosed |
| US-7758848-B2 | Cosmetic composition containing a polyorganosiloxane polymer | L'OREAL (FR) | 2010-07-20 | — | — | US | disclosed |
| US-20080057011-A1 | Composition structured with a polymer containing a heteroatom and an Organogelator | L'OREAL S.A., | 2008-03-06 | — | — | US | disclosed |
| US-20040170586-A1 | Cosmetic composition containing a polyorganosiloxane polymer | L'OREAL (FR) | 2004-09-02 | — | — | US | disclosed |
| US-6726915-B2 | DIAMIDE COMPOUNDS RETAINING GOOD COSMETIC PROPERTIES, IN PARTICULAR A CERTAIN LEVEL OF | L'OREAL (FR) | 2004-04-27 | — | — | US | disclosed |
| WO-2003105788-A2 | CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM | L'OREAL (FR) | 2003-12-24 | — | — | WO | disclosed |
| US-20030129211-A9 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | L'OREAL S.A. (FR) | 2003-07-10 | — | — | US | disclosed |
| US-20030091520-A1 | Use of at least one polar additive in a cosmetic composition comprising a liquid fatty phase structured by at least one molecular organogelator, to impart a thixotropic character to the composition | L'OREAL (FR) | 2003-05-15 | — | — | US | disclosed |
| EP-1294342-A2 | COMPOSITION STRUCTURED WITH A POLYMER CONTAINING AHETEROATOM AND AN ORGANOGELATOR | L'OREAL (FR) | 2003-03-26 | — | — | EP | disclosed |
| US-20020150602-A1 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | LIVOREIL AUDE (FR) | 2002-10-17 | — | — | US | disclosed |
| WO-2002055030-A2 | COMPOSITION STRUCTURED WITH A POLYMER CONTAINING A HETEROATOM AND ORGANOGELATOR | OREAL (FR) | 2002-07-18 | — | — | WO | disclosed |
| WO-2002047628-A1 | COMPOSITION STRUCTURED WITH A POLYMER CONTAINING A HETEROATOM AND AN ORGANOGELATOR | L'ORÉAL (FR) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080057011-A1 | Composition structured with a polymer containing a heteroatom and an Organogelator | CUTA, FABP4, PARG | DNM1 4507/4885LPAR1 610/4885LPAR3 679/4885 |
| US-20030129211-A9 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | FAAH, HRH1, HRH4 | DNM1 4680/4885LPAR1 1103/4885LPAR3 1151/4885 |
| US-20040170586-A1 | Cosmetic composition containing a polyorganosiloxane polymer | CUTA, XPA, PRDX1 | DNM1 3928/4885LPAR1 912/4885LPAR3 822/4885 |
| US-20020150602-A1 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | FAAH, HRH1, HRH4 | DNM1 4680/4885LPAR1 1103/4885LPAR3 1151/4885 |
| US-20110189117-A1 | COSMETIC COMPOSITION CONTAINING A POLYORGANISILOXANE POLYMER | CUTA, PRDX1, PRXL2A | DNM1 4605/4885LPAR1 884/4885LPAR3 869/4885 |
| US-20030091520-A1 | Use of at least one polar additive in a cosmetic composition comprising a liquid fatty phase structured by at least one molecular organogelator, to impart a thixotropic character to the composition | PLIN3, CUTA, FABP4 | DNM1 4119/4885LPAR1 431/4885LPAR3 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.