Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628918 | 0.81 | CYP2C19 (0.39) | ALDH1A1LMNASMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL12378742 | 0.81 | LMNA (0.41) | LMNASMN1; SMN2ADRA2AKEAP1NFE2L2 | |
| SCHEMBL6548164 | 0.80 | LMNA (0.50) | LMNASMN1; SMN2OPRM1KEAP1NFE2L2 | |
| SCHEMBL1973389 | 0.79 | TAAR1 (0.44) | ALDH1A1LMNAADRA2ATSHR | |
| SCHEMBL12378749 | 0.77 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2KEAP1NFE2L2 | |
| SCHEMBL12378753 | 0.77 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2KEAP1NFE2L2MEN1 | |
| SCHEMBL12199145 | 0.77 | LMNA (0.53) | LMNASMN1; SMN2OPRM1MEN1KMT2A | |
| SCHEMBL17923689 | 0.77 | LMNA (0.53) | LMNASMN1; SMN2OPRM1MEN1KMT2A | |
| SCHEMBL12378757 | 0.75 | TDP1 (0.46) | LMNASMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL12378739 | 0.75 | CYP2D6 (0.56) | ALDH1A1LMNASMN1; SMN2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943200-B1 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | SPECIALTY COATING SYSTEMS INC (US) | 2014-09-10 | — | — | EP | disclosed |
| US-7994372-B2 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090186998-A1 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | SPECIALTY COATING SYSTEMS, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-20090010870-A1 | Hydrophobic Flourinated Polymer Surfaces | PHILIPPS-UNIVERSITAT MARBURG (DE) | 2009-01-08 | — | — | US | disclosed |
| US-7462750-B2 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2008-12-09 | — | — | US | disclosed |
| US-20070099019-A1 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090010870-A1 | Hydrophobic Flourinated Polymer Surfaces | HGF, PFN1, HACD3 | ALDH1A1 2092/4885HTR2A 1175/4885LMNA 3788/4885 |
| US-20070099019-A1 | Parylene variants and methods of synthesis and use | CDC73, PARN, PFAS | ALDH1A1 3048/4885HTR2A 378/4885LMNA 514/4885 |
| US-20090186998-A1 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | CDC73, PARN, PFAS | ALDH1A1 2365/4885HTR2A 488/4885LMNA 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.