SCHEMBL12394331

SCHEMBL12394331

Nc1cc(-c2ccc3c(c2)OCO3)ccc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.54
CTNNB1 P35222 1/20 0.52
ALDH1A1 P00352 3/20 0.51
MAPK1 P28482 1/20 0.51
TP53 P04637 2/20 0.51
DHODH Q02127 1/20 0.51
KDM4E B2RXH2 4/20 0.49
HPGD P15428 3/20 0.49
PKM P14618 2/20 0.49
CA12 O43570 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
KMT2A Q03164 4/20 0.48
RXFP1 Q9HBX9 2/20 0.48
MEN1 O00255 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
MC4R P32245 1/20 0.48
PPARG P37231 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29436316 0.81 PPM1B (0.75) PPM1BALDH1A1KDM4EHPGDPKM
SCHEMBL710309 0.81 PPM1B (0.75) PPM1BALDH1A1KDM4EHPGDPKM
SCHEMBL2270432 0.79 PRKCZ (0.46) ALDH1A1MAPK1TP53KDM4EHPGD
SCHEMBL23499274 0.79 PPM1B (0.79) PPM1BALDH1A1KDM4EHPGDPKM
SCHEMBL29908977 0.79 PPM1B (0.79) PPM1BALDH1A1KDM4EHPGDPKM
SCHEMBL5952330 0.78 KMT2A (0.56) ALDH1A1MAPK1KDM4EHPGDCA12
SCHEMBL7018429 0.78 ALDH1A1 (0.50) ALDH1A1MAPK1KDM4EHPGDPKM
SCHEMBL29590055 0.78 ALDH1A1 (0.50) ALDH1A1MAPK1KDM4EHPGDPKM
SCHEMBL17177763 0.77 PPM1B (0.70) PPM1BALDH1A1KDM4EHPGDPKM
SCHEMBL30314350 0.77 PPM1B (0.70) PPM1BALDH1A1KDM4EHPGDPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7999132-B2 Anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2011-08-16 US disclosed
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP26, MMP11 PPM1B 4343/4885CTNNB1 1347/4885ALDH1A1 645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.