Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | SDHB | P21912 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122701 | 0.89 | SDHB (0.41) | SLC6A9PTGS2PTGS1SDHBLMNA | |
| SCHEMBL127078 | 0.73 | ALDH1A1 (0.49) | TAS2R14NPC1RAB9ALMNASORT1 | |
| SCHEMBL122983 | 0.72 | TAS2R14 (0.40) | ACLYTAS2R14LMNASYK | |
| SCHEMBL126502 | 0.70 | GABRP (0.43) | TAS2R14NPC1RAB9ASYK | |
| SCHEMBL973466 | 0.68 | SYK (0.37) | TAS2R14SYK | |
| SCHEMBL125060 | 0.66 | GFER (0.39) | KDM1ALMNASORT1 | |
| SCHEMBL125372 | 0.65 | TUBB4A (0.45) | NPC1RAB9ASDHBLMNA | |
| SCHEMBL1498329 | 0.65 | LMNA (0.41) | ACLYTAS2R14PTGS2NPC1RAB9A | |
| SCHEMBL6218067 | 0.65 | ACLY (0.44) | ACLYTAS2R14NPC1RAB9AKDM1A | |
| SCHEMBL28795121 | 0.64 | TUBB4A (0.47) | SDHBLMNATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102006777-B | Herbicidal compounds | SYNGENTA LTD | 2015-04-01 | — | — | CN | disclosed |
| US-8461083-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2013-06-11 | — | — | US | disclosed |
| EP-2265120-B1 | HERBICIDAL COUMPOUNDS | SYNGENTA LTD (GB) | 2012-03-07 | — | — | EP | disclosed |
| CN-102006777-A | Herbicidal coumpounds | SYNGENTA LTD | 2011-04-06 | — | — | CN | disclosed |
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2265120-A1 | HERBICIDAL COUMPOUNDS | Syngenta Limited (GB) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009115788-A1 | HERBICIDAL COUMPOUNDS | SYNGENTA LIMITED (GB) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | RDX, NQO2, DDT | ACLY 197/4885TAS2R14 4099/4885SLC6A9 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.