Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28987475 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPK1HDAC1HDAC6 | |
| SCHEMBL11373230 | 0.78 | MAPK1 (0.38) | ALDH1A1TSHRMAPK1HDAC1HDAC6 | |
| SCHEMBL11366813 | 0.76 | LMNA (0.40) | ALDH1A1TSHRMAPK1HDAC1HDAC6 | |
| SCHEMBL16285083 | 0.76 | ZDHHC20 (0.44) | ALDH1A1TSHRMAPK1HDAC1HDAC6 | |
| SCHEMBL12387739 | 0.75 | KDM4E (0.44) | ALDH1A1TSHRLMNAGAATP53 | |
| SCHEMBL25489016 | 0.74 | CA14 (0.51) | ALDH1A1TSHRMAPK1HDAC1HDAC6 | |
| SCHEMBL224145 | 0.73 | HDAC1 (0.39) | ALDH1A1TSHRMAPK1HDAC1HDAC6 | |
| SCHEMBL17174826 | 0.72 | ADRB2 (0.44) | ALDH1A1TSHRMAPK1MMP1MMP2 | |
| SCHEMBL11379890 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1HDAC1HDAC6 | |
| SCHEMBL31664518 | 0.72 | MMP1 (0.47) | ALDH1A1TSHRHDAC1HDAC6MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170183365-A1 | MACROCYCLES | LUMIPHORE, INC. | 2017-06-29 | — | — | US | disclosed |
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| US-20110189088-A1 | RADIOPHARMACEUTICAL COMPLEXES | LUMIPHORE, INC. (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110189088-A1 | RADIOPHARMACEUTICAL COMPLEXES | SLC39A3, SLC30A5, SLC40A1 | ALDH1A1 3214/4885TSHR 238/4885MAPK1 4867/4885 |
| US-20160221971-A1 | DI-MACROCYCLES | DLD, NDC1, MCL1 | ALDH1A1 1827/4885TSHR 1461/4885MAPK1 4795/4885 |
| US-20170183365-A1 | MACROCYCLES | HCCS, ABCB7, AURKAIP1 | ALDH1A1 1863/4885TSHR 1004/4885MAPK1 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.