Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 5/20 | 0.34 |
| ▸ | FNTB | P49356 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17079017 | 0.72 | ACHE (0.47) | MAPTKDM4EALDH1A1GAAACHE | |
| SCHEMBL7691593 | 0.71 | POLB (0.37) | FNTAFNTBKMT2AMEN1 | |
| SCHEMBL6192228 | 0.69 | PNMT (0.50) | — | |
| SCHEMBL6192806 | 0.66 | PNMT (0.37) | HTR2C | |
| SCHEMBL27855037 | 0.66 | HSD11B1 (0.56) | HSD11B1CDC7SIRT2SIRT1LMNA | |
| SCHEMBL10684249 | 0.64 | MTNR1A (0.50) | KMT2AMEN1 | |
| SCHEMBL4195851 | 0.64 | HSD11B1 (0.61) | HSD11B1CDC7SIRT2SIRT1KDM4E | |
| SCHEMBL26613393 | 0.64 | ESR1 (0.55) | SIRT2HTR2CMAPTKMT2ALMNA | |
| SCHEMBL2321696 | 0.63 | HTR7 (0.38) | MAPTKMT2ALMNAKDM4EMEN1 | |
| SCHEMBL12450086 | 0.63 | PNMT (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097946-A1 | OXAZOLIDINONE COMPOUNDS CONTAINING RING-FUSED BICYCLIC RING, PREPARATION METHOD AND USE THEREOF | 山东轩竹医药科技有限公司 (CN) | 2011-08-18 | — | — | WO | disclosed |
| CN-102153547-A | Oxazolidinone antibiotic containing parallel rings | SHANDONG XUANZHU PHARMACEUTICAL CO LTD OWN | 2011-08-17 | — | — | CN | disclosed |