SCHEMBL1245044

SCHEMBL1245044

CC(C)[C@@H]1CC[C@@H](C)[C@H](O)C1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.45
TRPM8 Q7Z2W7 2/20 0.45
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12449332 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
SCHEMBL2151294 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
SCHEMBL2162465 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
SCHEMBL31571716 1.00 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
SCHEMBL15369721 0.83 CA1 (0.46) TRPA1TRPM8CA1CA2CA4
SCHEMBL6757779 0.83 CA1 (0.46) TRPA1TRPM8CA1CA2CA4
SCHEMBL6757782 0.83 CA1 (0.46) TRPA1TRPM8CA1CA2CA4
SCHEMBL6757777 0.83 CA1 (0.46) TRPA1TRPM8CA1CA2CA4
SCHEMBL15369688 0.83 CA1 (0.46) TRPA1TRPM8CA1CA2CA4
SCHEMBL6757780 0.83 CA1 (0.46) TRPA1TRPM8CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3821225-B1 FIXATIVE SOLUTION AND METHOD OF PREPARATION OF BIOLOGICAL SAMPLE APACOR LTD (GB) 2023-07-05 EP claimed
US-12601660-B2 Fixative solution and method of preparation of biological sample APACOR LIMITED (GB) 2026-04-14 US disclosed
US-20260014098-A1 FENCHOL AS A STIMULATOR OF FREE FATTY ACID RECEPTOR AND OTHER USES THEREOF UNIV SOUTH FLORIDA (US) 2026-01-15 US disclosed
US-12447135-B2 Fenchol as a stimulator of free fatty acid receptor and other uses thereof UNIVERSITY OF SOUTH FLORIDA (US) 2025-10-21 US disclosed
US-20250290009-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING FIRMENICH SA (CH) 2025-09-18 US disclosed
US-20250137015-A1 YEAST PLATFORM FOR RENEWABLE INDUSTRIAL TERPENE PRODUCTION Wang, Zhen (US) 2025-05-01 US disclosed
EP-4522714-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING Firmenich SA (CH) 2025-03-19 EP disclosed
CN-119173616-A Recovery of novel low sulfur terpene mixtures from wood processing 弗门尼舍有限公司 2024-12-20 CN disclosed
US-20240410055-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2024-12-12 US disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
CN-110891615-B System and method for selecting and releasing fragrance 阿甘香气及精细化学有限公司 2022-08-05 CN disclosed
WO-2022129608-A2 ENZYMES AND METHODS FOR FERMENTATIVE PRODUCTION OF MONOTERPENE ESTERS ISOBIONICS B.V. (NL) 2022-06-23 WO disclosed
EP-4015626-A1 ENZYMES AND METHODS FOR FERMENTATIVE PRODUCTION OF MONOTERPENE ESTERS Isobionics B.V. (NL) 2022-06-22 EP disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed
EP-2292224-B1 Derivatives of lactiosole for preventing or treating diabetes SYMRISE AG (DE) 2018-03-07 EP disclosed
CN-106999972-A System and method for discharging fragrance 阿甘芳香和精细化工有限公司 2017-08-01 CN disclosed
US-8592621-B2 Precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease SYMRISE AG (DE) 2013-11-26 US disclosed
EP-2292224-A1 Precursor compounds of sweet receptor antagonists for preventing or treating diabetes Symrise AG (DE) 2011-03-09 EP disclosed
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE SYMRISE GMBH CO. KG (DE) 2011-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12601660-B2 Fixative solution and method of preparation of biological sample CA3, CA2, CA1 TRPA1 421/4885TRPM8 288/4885CA1 3/4885
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 TRPA1 179/4885TRPM8 180/4885CA1 1475/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 TRPA1 179/4885TRPM8 180/4885CA1 1475/4885
US-20260014098-A1 FENCHOL AS A STIMULATOR OF FREE FATTY ACID RECEPTOR AND OTHER USES THEREOF FFAR2, FFAR1, FFAR3 TRPA1 605/4885TRPM8 651/4885CA1 3069/4885
US-12447135-B2 Fenchol as a stimulator of free fatty acid receptor and other uses thereof FFAR2, FFAR1, FFAR3 TRPA1 1911/4885TRPM8 1388/4885CA1 2613/4885
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE TAS1R2, TAS2R5, TAS2R1 TRPA1 241/4885TRPM8 132/4885CA1 3071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.