SCHEMBL124825

SCHEMBL124825

c1ccc2c(-c3c4ccccc4c(-c4cccc5c4sc4ccccc45)c4ccccc34)cccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.49
PARP14 Q460N5 1/20 0.46
GPR3 P46089 1/20 0.43
PRKDC P78527 7/20 0.38
PIK3CD O00329 2/20 0.38
PIK3CB P42338 2/20 0.38
MAPT P10636 2/20 0.38
DHFR P00374 1/20 0.37
BRD4 O60885 1/20 0.36
PIK3CA P42336 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36
KCNH2 Q12809 1/20 0.36
BRDT Q58F21 1/20 0.36
TYMP P19971 1/20 0.36
MEN1 O00255 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124836 0.93 ALOX5 (0.47) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL17943954 0.93 ALOX5 (0.45) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL20334558 0.92 ALOX5 (0.52) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL9890847 0.91 ALOX5 (0.56) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL22706403 0.91 ALOX5 (0.51) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL17539985 0.89 ALOX5 (0.54) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL124835 0.89 ALOX5 (0.50) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL21450764 0.89 ALOX5 (0.54) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL10122720 0.89 ALOX5 (0.46) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL23426608 0.88 ALOX5 (0.38) ALOX5PARP14GPR3DHFRTYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4291000-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS Kunshan Go-Visionox Opto-Electronics Co., Ltd. (CN) 2023-12-13 EP disclosed
US-20230225144-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
US-20230225144-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
WO-2023125276-A1 ORGANIC COMPOUND AND USE THEREOF 北京鼎材科技有限公司 2023-07-06 WO disclosed
US-20230200219-A1 A compound, an organic electroluminescent device and a display device BEIJING ETERNAL MATERIAL TECHNOLOGY CO., LTD (CN) 2023-06-22 US disclosed
US-20230200219-A1 A compound, an organic electroluminescent device and a display device BEIJING ETERNAL MATERIAL TECHNOLOGY CO., LTD (CN) 2023-06-22 US disclosed
US-20230172054-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed
US-20230172054-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed
WO-2023093094-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS 昆山国显光电有限公司 2023-06-01 WO disclosed
US-20230096132-A1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-03-30 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
EP-2423179-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME Idemitsu Kosan Co., Ltd. (JP) 2012-02-29 EP disclosed
EP-2423206-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME Idemitsu Kosan Co., Ltd. (JP) 2012-02-29 EP disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230096132-A1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND LAGE3, ELOC, ELOB ALOX5 496/4885PARP14 2405/4885GPR3 3023/4885
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AOC2, AOC3, H1-4 ALOX5 3902/4885PARP14 3386/4885GPR3 1447/4885
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AR, H1-4, AFF4 ALOX5 3494/4885PARP14 708/4885GPR3 1171/4885
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same H1-4, H1-2, H1-0 ALOX5 4030/4885PARP14 1457/4885GPR3 797/4885
US-20230200219-A1 A compound, an organic electroluminescent device and a display device L1CAM, VDAC2, CD274 ALOX5 1763/4885PARP14 714/4885GPR3 2243/4885
US-20230172054-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE CRY1, CRY2, CHRM1 ALOX5 1512/4885PARP14 1978/4885GPR3 2025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.