Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | LDHB | P07195 | 1/20 | 0.40 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499380 | 0.86 | AADAT (0.41) | AADATPTGER4PTGER2MEN1KMT2A | |
| SCHEMBL12499656 | 0.85 | MAPT (0.43) | LMNAPOLBIDH1MEN1KMT2A | |
| SCHEMBL12499324 | 0.85 | MAPT (0.40) | LMNAPOLBLDHALDHBMEN1 | |
| SCHEMBL12498729 | 0.84 | SRD5A2 (0.46) | SRD5A2LMNAPOLBLDHALDHB | |
| SCHEMBL12499736 | 0.84 | SRD5A2 (0.46) | SRD5A2LMNAPOLBLDHALDHB | |
| SCHEMBL12499865 | 0.80 | CCR2 (0.37) | KDM5AKDM5BPTGER4PTGER2MEN1 | |
| SCHEMBL12498775 | 0.76 | HCAR2 (0.42) | LMNAKDM4CKDM5BPTGER4PTGER2 | |
| SCHEMBL12499839 | 0.73 | LMNA (0.43) | SRD5A2LMNAPOLBAADATIDH1 | |
| SCHEMBL12499319 | 0.73 | KDM4E (0.43) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL12499378 | 0.72 | MAPT (0.40) | LMNAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103071-A2 | COMPOUNDS AND COMPOSITIONS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-08-02 | — | — | WO | disclosed |