Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | PDE1A | P54750 | 2/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499865 | 0.86 | CCR2 (0.37) | KMT2AMEN1 | |
| SCHEMBL12498775 | 0.85 | HCAR2 (0.42) | MAPTADRA1AHRH1ADRA1BLMNA | |
| SCHEMBL12499317 | 0.85 | SRD5A2 (0.43) | LDHALDHBLMNAKMT2APOLB | |
| SCHEMBL12499698 | 0.84 | MAPT (0.47) | MAPTKDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL12499400 | 0.81 | VDR (0.49) | MAPTKDM4EVDRADRA1AHRH1 | |
| SCHEMBL12499378 | 0.80 | MAPT (0.40) | MAPTKDM4EVDRADRA1AHRH1 | |
| SCHEMBL12499380 | 0.76 | AADAT (0.41) | MAPTKMT2ARAB9ANPC1MEN1 | |
| SCHEMBL14937851 | 0.73 | KDM4E (0.34) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12499589 | 0.72 | ALOX5 (0.43) | MAPTKDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL12499656 | 0.71 | MAPT (0.43) | MAPTKDM4ELMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103071-A2 | COMPOUNDS AND COMPOSITIONS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-08-02 | — | — | WO | disclosed |