Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12498677 | 0.87 | PLA2G2A (0.45) | PLA2G2AKMT2ARAB9AMEN1LMNA | |
| SCHEMBL3718927 | 0.86 | ALDH1A1 (0.47) | PLA2G2AKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL12499730 | 0.86 | TSHR (0.44) | PLA2G2AKMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL12498726 | 0.85 | HSP90AA1 (0.47) | PLA2G2AKMT2ARAB9AMEN1LMNA | |
| SCHEMBL12499400 | 0.85 | VDR (0.49) | KMT2ARAB9AMEN1LMNAHTT | |
| SCHEMBL12499839 | 0.84 | LMNA (0.43) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL12499851 | 0.83 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL12498769 | 0.75 | GPR52 (0.44) | KMT2AMEN1HTTSMN1; SMN2MAPT | |
| SCHEMBL12498738 | 0.73 | MAPT (0.47) | KMT2ARAB9AMEN1LMNAHTT | |
| SCHEMBL12499698 | 0.73 | MAPT (0.47) | KMT2ARAB9ALMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103071-A2 | COMPOUNDS AND COMPOSITIONS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-08-02 | — | — | WO | disclosed |