Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13757097 | 0.89 | TSHR (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2A | |
| SCHEMBL2374703 | 0.78 | MAOA (0.54) | MAOAMAOBOPRM1 | |
| SCHEMBL27825443 | 0.77 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2A | |
| SCHEMBL8881428 | 0.76 | MEN1 (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2A | |
| SCHEMBL13936275 | 0.74 | ALDH1A1 (0.44) | SLC6A2SLC6A4SLC6A3CYP2D6MAOA | |
| SCHEMBL6633817 | 0.74 | MAOA (0.62) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2A | |
| SCHEMBL4974150 | 0.74 | MAOA (0.62) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2A | |
| SCHEMBL5509592 | 0.74 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2A | |
| SCHEMBL6672640 | 0.74 | MAOA (0.50) | MAOAMAOBOPRM1 | |
| SCHEMBL5639001 | 0.74 | MAOA (0.50) | SLC6A2SLC6A4SLC6A3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12240854-B2 | TRAF 6 inhibitors | HELMHOLTZ ZENTRUM MUENCHEN—DEUTSCHES FORSCHUNGSZENTRUM FUERGESUNDHEIT UND UMWELT (GMBH) (DE) | 2025-03-04 | — | — | US | disclosed |
| EP-3768678-A1 | TRAF 6 INHIBITORS | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2021-01-27 | — | — | EP | disclosed |
| US-20210017183-A1 | TRAF 6 INHIBITORS | HELMHOLTZ ZENTRUM MUENCHEN - DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT (GMBH) (DE) | 2021-01-21 | — | — | US | disclosed |
| US-20210017183-A1 | TRAF 6 INHIBITORS | HELMHOLTZ ZENTRUM MUENCHEN - DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT (GMBH) (DE) | 2021-01-21 | — | — | US | disclosed |
| WO-2019180207-A1 | TRAF 6 INHIBITORS | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019180207-A1 | TRAF 6 INHIBITORS | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2019-09-26 | — | — | WO | disclosed |
| US-8828985-B2 | Carbamate and urea inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 | VITAE PHARMACEUTICALS, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| US-20130244994-A1 | CARBAMATE AND UREA INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 | CLAREMON DAVID A (US) | 2013-09-19 | — | — | US | disclosed |
| US-8399504-B2 | Carbamate and urea inhibitors of 11Beta-hydroxysteroid dehydrogenase 1 | VITAE PHARMACEUTICALS, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20110112062-A1 | Carbamate And Urea Inhibitors Of 11Beta-Hydroxysteroid Dehydrogenase 1 | VITAE PHARMACEUTICALS, INC | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130244994-A1 | CARBAMATE AND UREA INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 | HSD11B1, HSD3B1, HSD17B1 | SLC6A2 3331/4885SLC6A4 3723/4885SLC6A3 3498/4885 |
| US-12240854-B2 | TRAF 6 inhibitors | TRAF2, TRAF6, TRAFD1 | SLC6A2 2292/4885SLC6A4 3441/4885SLC6A3 2106/4885 |
| US-20210017183-A1 | TRAF 6 INHIBITORS | TRAF2, TRAF6, TRAFD1 | SLC6A2 2292/4885SLC6A4 3441/4885SLC6A3 2106/4885 |
| US-20110112062-A1 | Carbamate And Urea Inhibitors Of 11Beta-Hydroxysteroid Dehydrogenase 1 | HSD11B1, HSD3B1, HSD17B1 | SLC6A2 2729/4885SLC6A4 2980/4885SLC6A3 2933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.