SCHEMBL126116

SCHEMBL126116

Brc1ccc(C2CCCCC2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
HDAC1 Q13547 1/20 0.48
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HTT P42858 2/20 0.44
LMNA P02545 1/20 0.44
HDAC3 O15379 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
KDM1A O60341 5/20 0.43
KCNH2 Q12809 2/20 0.43
MAOB P27338 2/20 0.43
RCOR1 Q9UKL0 2/20 0.43
NOTUM Q6P988 2/20 0.43
HSP90AA1 P07900 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17061138 1.00 HDAC8 (0.48) HDAC8HDAC6HDAC1NPC1RAB9A
SCHEMBL21609716 1.00 HDAC8 (0.48) HDAC8HDAC6HDAC1NPC1RAB9A
SCHEMBL3575917 0.97 HDAC8 (0.50) HDAC8HDAC6HDAC1NPC1RAB9A
SCHEMBL30056544 0.95 HDAC8 (0.48) HDAC8HDAC6HDAC1NPC1RAB9A
SCHEMBL233178 0.92 ESR2 (0.47) HDAC8HDAC6HDAC1KDM1AKCNH2
SCHEMBL25274751 0.88 HDAC8 (0.41) HDAC8HDAC6HDAC1NPC1RAB9A
Tetrahydrofuran SCHEMBL28669177 0.88 SMN1; SMN2 (0.47) HDAC8HDAC6HDAC1NPC1RAB9A
Pyrrolidine SCHEMBL9026279 0.88 CYP2D6 (0.45) HDAC8HDAC6HDAC1NPC1RAB9A
SCHEMBL265495 0.87 KDM1A (0.48) KDM1AKCNH2MAOBRCOR1MAPT
SCHEMBL14804315 0.87 KDM1A (0.48) KDM1AKCNH2MAOBRCOR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113880708-B Preparation method of 4-cyclohexylbenzoic acid 南京桦冠生物技术有限公司 2022-03-18 CN claimed
CN-113880708-A Preparation method of 4-cyclohexylbenzoic acid 南京桦冠生物技术有限公司 2022-01-04 CN claimed
US-7547810-B2 Coated catalyst for aromatic alkylation CATALYTIC DISTILLATION TECHNOLOGIES (US) 2009-06-16 US claimed
US-20090023969-A1 COATED CATALYST FOR AROMATIC ALKYLATION CATALYTIC DISTILLATION TECHNOLOGIES (US) 2009-01-22 US claimed
CN-1938894-A Nonaqueous electrolyte solution and lithium secondary battery UBE INDUSTRIES (JP) 2007-03-28 CN claimed
JP-59059635-A None JP disclosed
US-20260124197-A1 NOVEL HETEROBICYCLIC COMPOUND FOR INHIBITING YAP-TEAD INTERACTION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME HANMI PHARMACEUTICAL CO LTD (KR) 2026-05-07 US disclosed
EP-4215537-B1 LIGAND COMPOUND, ORGANOCHROMIUM COMPOUND, AND CATALYST SYSTEM COMPRISING THE SAME LG CHEMICAL LTD (KR) 2026-04-29 EP disclosed
US-12577195-B2 Light emitting element and display device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2026-03-17 US disclosed
US-20260049050-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO LTD (KR) 2026-02-19 US disclosed
US-20260033237-A1 AMINE COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING SAME SAMSUNG DISPLAY CO LTD (KR) 2026-01-29 US disclosed
US-12497348-B2 Light emitting element and amine compound for the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-12-16 US disclosed
US-4849569-A Alkylation of organic aromatic compounds CHEMICAL RESEARCH & LICENSING COMPANY (US) 1989-07-18 US disclosed
EP-0189683-A1 Alkylation of organic aromatic compounds CHEMICAL RESEARCH & LICENSING COMPANY (US) 1986-08-06 EP disclosed
JP-S5959635-A 4,4'-SUBSTITUTED BIPHENYL DERIVATIVE SEIKO EPSON CORP 1984-04-05 JP disclosed
US-4112099-A FIBRINOLYTICS, THROMBOLYTICS, ANTIPHLOGISTICS, ANALGESICS CIBA-GEIGY CORPORATION (US) 1978-09-05 US disclosed
US-4076822-A ANTIINFLAMMATORY AGENTS CIBA-GEIGY CORPORATION (US) 1978-02-28 US disclosed
US-3992536-A SEDATIVES AND MUSCLE RELAXANTS BOEHRINGER INGELHEIM GMBH (DT) 1976-11-16 US disclosed
US-3980657-A FIBRINOLYTICS, THROMBOLYTICS, ANTIPHLOGISTICS, ANALGESICS CIBA-GEIGY CORPORATION (US) 1976-09-14 US disclosed
US-3931185-A SEDATIVES, MUSCLE RELAXANT BOEHRINGER INGELHEIM GMBH (DT) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260033237-A1 AMINE COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING SAME HCN1, CRY1, NAT1 HDAC8 2577/4885HDAC6 3471/4885HDAC1 499/4885
US-12497348-B2 Light emitting element and amine compound for the same NFE2L2, SLC1A2, ASIC1 HDAC8 3668/4885HDAC6 3828/4885HDAC1 1768/4885
US-20260124197-A1 NOVEL HETEROBICYCLIC COMPOUND FOR INHIBITING YAP-TEAD INTERACTION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME YAP1, RCC1, YES1 HDAC8 2078/4885HDAC6 683/4885HDAC1 992/4885
US-12577195-B2 Light emitting element and display device including the same STRA6, NR2E3, SLC29A1 HDAC8 4359/4885HDAC6 4690/4885HDAC1 4002/4885
US-20260049050-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME NR2E3, NR2E1, ESR2 HDAC8 2690/4885HDAC6 3296/4885HDAC1 860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.