Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | TKT | P29401 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612336 | 0.81 | IDO1 (0.61) | DAOIDO1 | |
| Hydrochloric Acid SCHEMBL20677852 | 0.79 | IDO1 (0.62) | IDO1 | |
| SCHEMBL14450873 | 0.75 | DAO (0.45) | DAOIDO1TRPV4KDM1AMAOA | |
| SCHEMBL13356156 | 0.72 | DAO (0.50) | DAOTRPV4KDM1AMAOAMAOB | |
| SCHEMBL1146015 | 0.72 | DAO (0.50) | DAOTRPV4KDM1AMAOAMAOB | |
| SCHEMBL688551 | 0.72 | DAO (0.50) | DAOTRPV4KDM1AMAOAMAOB | |
| SCHEMBL13633817 | 0.71 | IDO1 (0.60) | IDO1 | |
| SCHEMBL132198 | 0.69 | TRPV4 (0.52) | DAOTRPV4KDM1AMAOAMAOB | |
| SCHEMBL345116 | 0.69 | TRPV4 (0.52) | DAOTRPV4KDM1AMAOAMAOB | |
| SCHEMBL317731 | 0.69 | TRPV4 (0.52) | DAOTRPV4KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125412-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES LLC (US) | 2015-09-08 | — | — | US | disclosed |
| US-9012654-B2 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)-alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2015-04-21 | — | — | US | disclosed |
| US-20140135362-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2014-05-15 | — | — | US | disclosed |
| US-8669278-B2 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | DOW AGROSCIENCES, LLC. (US) | 2014-03-11 | — | — | US | disclosed |
| US-8507532-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES, LLC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20120329740-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120316067-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2012-12-13 | — | — | US | disclosed |
| US-7960354-B2 | Synergistic pesticidal mixtures | DOW AGROSCIENCES LLC (US) | 2011-06-14 | — | — | US | disclosed |
| US-20100168178-A1 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES, LLC | 2010-07-01 | — | — | US | disclosed |
| US-20100168177-A1 | Stable insecticide compositions | DOW AGROSCIENCES, LLC | 2010-07-01 | — | — | US | disclosed |
| US-20090325892-A1 | Synergistic pesticidal mixtures | DOW AGROSCIENCES LLC (US) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168178-A1 | Stable insecticide compositions and methods for producing same | DDT, AGPS, SMOX | DAO 73/4885IDO1 1135/4885TRPV4 3905/4885 |
| US-20100168177-A1 | Stable insecticide compositions | DDT, PIR, SPOUT1 | DAO 79/4885IDO1 178/4885TRPV4 2049/4885 |
| US-20120316067-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | PRDX6, DDT, HDHD5 | DAO 247/4885IDO1 239/4885TRPV4 2204/4885 |
| US-20120329740-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | PRDX6, DDT, HDHD5 | DAO 247/4885IDO1 239/4885TRPV4 2204/4885 |
| US-20090325892-A1 | Synergistic pesticidal mixtures | ACHE, DDT, PDE1C | DAO 2015/4885IDO1 312/4885TRPV4 792/4885 |
| US-20140135362-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | NPEPPS, HDHD5, PRDX6 | DAO 163/4885IDO1 218/4885TRPV4 1763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.