Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MMP12 | P39900 | 2/20 | 0.50 |
| ▸ | UQCRB | P14927 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 7/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4804640 | 0.81 | ADAMTS4 (0.51) | MMP1GAAMMP12UQCRBMAPK1 | |
| SCHEMBL29039629 | 0.77 | ADAMTS4 (0.47) | MMP1GAAMMP12UQCRBMAPK1 | |
| SCHEMBL1784104 | 0.77 | ADAMTS4 (0.55) | MMP1GAAMMP12UQCRBMAPK1 | |
| SCHEMBL13485822 | 0.75 | MMP2 (0.78) | MMP1GAAMMP12UQCRBMAPK1 | |
| SCHEMBL7946395 | 0.75 | KMT2A (0.61) | MMP1GAAMMP12UQCRBMAPK1 | |
| SCHEMBL28937576 | 0.74 | MMP1 (0.47) | MMP1GAAMMP12UQCRBMAPK1 | |
| SCHEMBL4802135 | 0.74 | MMP1 (0.55) | MMP1GAAMMP12UQCRBMAPK1 | |
| SCHEMBL10780756 | 0.74 | MMP1 (0.55) | MMP1GAAMMP12UQCRBMAPK1 | |
| SCHEMBL3906959 | 0.74 | NR3C2 (0.61) | MMP1GAAMMP12UQCRBMAPK1 | |
| SCHEMBL417467 | 0.74 | CA1 (0.59) | MMP1GAAMMP12UQCRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124653-A1 | ARYL-SULPHONAMIDIC DIMERS AS METALLOPROTEASES INHIBITORS | BRACCO IMAGING S.P.A. (IT) | 2011-05-26 | — | — | US | disclosed |
| US-20110117015-A1 | Diagnostic Agents Selective Against Metalloproteases | BRACCO IMAGING S.P.A. (IT) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124653-A1 | ARYL-SULPHONAMIDIC DIMERS AS METALLOPROTEASES INHIBITORS | MMP9, MMP1, MMP2 | MMP1 2/4885GAA 209/4885MMP12 11/4885 |
| US-20110117015-A1 | Diagnostic Agents Selective Against Metalloproteases | MMP3, MMP7, MMP9 | MMP1 4/4885GAA 153/4885MMP12 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.