Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175653 | 0.91 | THRB (0.42) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL5571975 | 0.84 | PLA2G2A (0.33) | ALDH1A1HTTPLA2G2AL3MBTL1PPARG | |
| SCHEMBL9547571 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HSD17B10PTPN11PPARGPPARA | |
| SCHEMBL1020562 | 0.81 | HTT (0.51) | TSHRALDH1A1THRBHTTPRKCG | |
| SCHEMBL29507099 | 0.81 | THRB (0.47) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL9547579 | 0.80 | F13A1 (0.39) | ALDH1A1PTPN11PPARGPPARA | |
| SCHEMBL9547648 | 0.80 | F13A1 (0.39) | ALDH1A1PTPN11PPARGPPARA | |
| SCHEMBL11899588 | 0.80 | F13A1 (0.39) | ALDH1A1PTPN11PPARGPPARA | |
| SCHEMBL11899221 | 0.80 | F13A1 (0.39) | ALDH1A1PTPN11PPARGPPARA | |
| SCHEMBL9547634 | 0.80 | F13A1 (0.39) | ALDH1A1PTPN11PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11207247-B2 | Low water-sensitive dental composition | SHOFU INC. (JP) | 2021-12-28 | — | — | US | disclosed |
| US-20210007938-A1 | LOW WATER-SENSITIVE DENTAL COMPOSITION | SHOFU INC. (JP) | 2021-01-14 | — | — | US | disclosed |
| EP-3733151-A1 | LOW-WATER-SENSITIVE DENTAL COMPOSITION | Shofu Inc. (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-8183306-B2 | Two-paste type dental self-adhesive resin cement | KABUSHIKI KAISHA SHOFU (JP) | 2012-05-22 | — | — | US | disclosed |
| US-7879924-B2 | Dental composite resin cement, dental primer and dental adhesive kit containing them | KABUSHIKI KAISHA SHOFU (JP) | 2011-02-01 | — | — | US | disclosed |
| US-20100010115-A1 | Two-paste type dental self-adhesive resin cement | KABUSHIKI KAISHA SHOFU (JP) | 2010-01-14 | — | — | US | disclosed |
| US-20090048366-A1 | Dental Composite Resin Cement, Dental Primer and Dental Adhesive Kit Containing Them | KABUSHIKI KAISHA SHOFU (JP) | 2009-02-19 | — | — | US | disclosed |
| US-5264513-A | Dental adhesive | KABUSHIKI KAISHA SHOFU (JP) | 1993-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048366-A1 | Dental Composite Resin Cement, Dental Primer and Dental Adhesive Kit Containing Them | CDH1, JMJD7, WDR91 | TSHR 4536/4885ALDH1A1 627/4885CYP3A4 4752/4885 |
| US-20210007938-A1 | LOW WATER-SENSITIVE DENTAL COMPOSITION | MGMT, DNMT3A, TAS2R1 | TSHR 3563/4885ALDH1A1 821/4885CYP3A4 3926/4885 |
| US-11207247-B2 | Low water-sensitive dental composition | MGMT, DNMT3A, TAS2R1 | TSHR 3563/4885ALDH1A1 821/4885CYP3A4 3926/4885 |
| US-20100010115-A1 | Two-paste type dental self-adhesive resin cement | CDH1, PTK2, CAD | TSHR 4807/4885ALDH1A1 656/4885CYP3A4 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.