Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162878 | 1.00 | MMP13 (0.39) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL953166 | 1.00 | MMP13 (0.39) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL66573 | 0.86 | HDAC1 (0.41) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL67491 | 0.86 | HDAC1 (0.41) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL20826464 | 0.86 | HDAC1 (0.41) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL626316 | 0.85 | AAK1 (0.39) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL13335431 | 0.85 | AAK1 (0.36) | MMP13AAK1HDAC6CTSSCTSK | |
| SCHEMBL7401175 | 0.85 | MMP13 (0.39) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL626315 | 0.85 | AAK1 (0.39) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL7401177 | 0.85 | MMP13 (0.39) | MMP13AAK1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235719-A1 | DIMERIC SMAC MIMETICS USEFUL IN HIV THERAPY | VIIV HEALTHCARE COMPANY (US) | 2025-11-13 | — | — | WO | disclosed |
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2025-09-25 | — | — | US | disclosed |
| US-20250281433-A1 | NOVEL DERIVATIVE COMPOUND HAVING BIPHENYL GROUP INTRODUCED INTO AMINO-ALKANOIC ACID AND ANTI-INFLAMMATORY COMPOSITION COMPRISING SAME | AMTIXBIO CO., LTD. (KR) | 2025-09-11 | — | — | US | disclosed |
| US-12338230-B2 | Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| US-20250129099-A1 | INHIBITOR OF APOPTOSIS (IAP) PROTEIN ANTAGONISTS | Sanford Burnham Prebys Medical Discovery Institute | 2025-04-24 | — | — | US | disclosed |
| US-20250074887-A1 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF | Sea Pharmaceuticals LLC. (US) | 2025-03-06 | — | — | US | disclosed |
| US-12180139-B2 | Method for preparing aminoalkanoic acid derivative containing biphenyl group | AMTIXBIO CO., LTD. (KR) | 2024-12-31 | — | — | US | disclosed |
| US-12172945-B2 | Aminoalkanoic acid derivative containing biphenyl group and use of the same | AMTIXBIO CO., LTD. (KR) | 2024-12-24 | — | — | US | disclosed |
| US-12129220-B2 | Pharmaceutical composition comprising aminoalkanoic acid derivative containing biphenyl group | AMTIXBIO CO., LTD. (KR) | 2024-10-29 | — | — | US | disclosed |
| CN-118845786-A | Combination therapy | 詹森药业有限公司 | 2024-10-29 | — | — | CN | disclosed |
| US-20090069294-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-03-12 | — | — | US | disclosed |
| CN-101305019-A | New cyclic peptide compounds | ASTELLAS PHARMA INC (JP) | 2008-11-12 | — | — | CN | disclosed |
| US-20080242658-A1 | Inhibitors of Iap | NOVARTIS AG (CH) | 2008-10-02 | — | — | US | disclosed |
| US-7419975-B2 | Organic compounds | NOVARTIS AG (CH) | 2008-09-02 | — | — | US | disclosed |
| EP-1902065-A2 | CYCLIC AMIDE DERIVATIVES INHIBITORS OF THE INHIBITOR OF APOPTOSIS PROTEINS, THEIR PREPARATION, AND THEIR USE | Novartis AG (CH) | 2008-03-26 | — | — | EP | disclosed |
| CN-1964970-A | Inhibitors of IAP | NOVARTIS AG (CH) | 2007-05-16 | — | — | CN | disclosed |
| EP-1735307-A1 | INHIBITORS OF IAP | Novartis AG (CH) | 2006-12-27 | — | — | EP | disclosed |
| WO-2006133147-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-12-14 | — | — | WO | disclosed |
| US-20050234042-A1 | Organic compounds | PALERMO MARK G | 2005-10-20 | — | — | US | disclosed |
| WO-2005097791-A1 | INHIBITORS OF IAP | NOVARTIS AG (CH) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069294-A1 | Organic Compounds | XIAP, BAX, MCL1 | MMP13 4022/4885AAK1 4071/4885MEN1 2628/4885 |
| US-20080242658-A1 | Inhibitors of Iap | XIAP, BIRC2, BIRC5 | MMP13 2973/4885AAK1 1072/4885MEN1 2598/4885 |
| US-12172945-B2 | Aminoalkanoic acid derivative containing biphenyl group and use of the same | GABBR1, AADAC, GABBR2 | MMP13 2970/4885AAK1 1582/4885MEN1 4071/4885 |
| US-20250129099-A1 | INHIBITOR OF APOPTOSIS (IAP) PROTEIN ANTAGONISTS | API5, XIAP, BIRC5 | MMP13 2193/4885AAK1 664/4885MEN1 1418/4885 |
| US-20250074887-A1 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF | GABRQ, GRIK5, CYP3A7 | MMP13 2519/4885AAK1 4341/4885MEN1 1622/4885 |
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | MMP13 3972/4885AAK1 1629/4885MEN1 2820/4885 |
| US-12338230-B2 | Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders | CFD, TFPI, CFH | MMP13 2325/4885AAK1 2305/4885MEN1 2099/4885 |
| US-20050234042-A1 | Organic compounds | AIFM1, BAX, API5 | MMP13 3703/4885AAK1 2295/4885MEN1 3135/4885 |
| US-12180139-B2 | Method for preparing aminoalkanoic acid derivative containing biphenyl group | AKR7A2, CYP51A1, APEH | MMP13 2896/4885AAK1 1701/4885MEN1 3516/4885 |
| US-20250281433-A1 | NOVEL DERIVATIVE COMPOUND HAVING BIPHENYL GROUP INTRODUCED INTO AMINO-ALKANOIC ACID AND ANTI-INFLAMMATORY COMPOSITION COMPRISING SAME | AADAT, AADAC, AHR | MMP13 315/4885AAK1 1778/4885MEN1 4383/4885 |
| US-12129220-B2 | Pharmaceutical composition comprising aminoalkanoic acid derivative containing biphenyl group | AHR, AADAC, GABBR1 | MMP13 2426/4885AAK1 2040/4885MEN1 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.