SCHEMBL12758151

SCHEMBL12758151

CC1(C)c2ccccc2-c2sccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.38
HTR2A P28223 3/20 0.38
CHRM2 P08172 2/20 0.38
ADRA2A P08913 2/20 0.38
CHRM1 P11229 2/20 0.38
ADRA2B P18089 2/20 0.38
ADRA2C P18825 2/20 0.38
CHRM3 P20309 2/20 0.38
DRD1 P21728 2/20 0.38
HTR2C P28335 2/20 0.38
ADRA1A P35348 2/20 0.38
HRH1 P35367 2/20 0.38
DRD3 P35462 2/20 0.38
HTR2B P41595 2/20 0.38
HTR3A P46098 2/20 0.38
KCNH2 Q12809 2/20 0.38
MLNR O43193 1/20 0.38
NR1I2 O75469 1/20 0.38
ADRB1 P08588 1/20 0.38
HTR1A P08908 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50526 0.80 CES1 (0.35) CES1
SCHEMBL17068313 0.79 CES1 (0.33) PGRCES1
SCHEMBL9927262 0.78 PTPRC (0.39) PTPRCMEN1KMT2ACES1LMNA
SCHEMBL17108437 0.75 CES1 (0.33) CES1
SCHEMBL283246 0.75 HTR2A (0.48) HTR2ACHRM2ADRA2ACHRM1ADRA2B
SCHEMBL29363404 0.75 HTR2A (0.48) HTR2ACHRM2ADRA2ACHRM1ADRA2B
SCHEMBL22503337 0.74 CES1 (0.30) CES1
SCHEMBL20850166 0.74 ALDH1A1 (0.33) MEN1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL23568686 0.74 TDP2 (0.33) PDK2
SCHEMBL20850099 0.74 CASP3 (0.37) HTR2AHTR2CPGRLMNAPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10370473-B2 Compound, curable composition, cured product, optical member, and lens FUJIFILM CORPORATION (JP) 2019-08-06 US disclosed
US-8502209-B2 Polymer compound and organic transistor using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-06 US disclosed
US-8502209-B2 Polymer compound and organic transistor using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-06 US disclosed
US-20110073854-A1 POLYMER COMPOUND AND ORGANIC TRANSISTOR USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-31 US disclosed
US-20110073854-A1 POLYMER COMPOUND AND ORGANIC TRANSISTOR USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-31 US disclosed
EP-2289965-A1 POLYMER COMPOUND AND ORGANIC TRANSISTOR USING THE POLYMER COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110073854-A1 POLYMER COMPOUND AND ORGANIC TRANSISTOR USING THE SAME TERT, NOXO1, TERB1 PTPRC 2262/4885HTR2A 3983/4885CHRM2 988/4885
US-10370473-B2 Compound, curable composition, cured product, optical member, and lens CRYZ, CRYAA, UACA PTPRC 4576/4885HTR2A 3473/4885CHRM2 848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.