Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.62 |
| ▸ | APP | P05067 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.45 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337585 | 1.00 | THRB (0.62) | THRBAPPMEN1KMT2ATDP1 | |
| SCHEMBL117324 | 0.87 | THRB (0.58) | THRBAPPMEN1KMT2ATDP1 | |
| SCHEMBL1598800 | 0.86 | THRB (0.60) | THRBAPPMEN1KMT2ATDP1 | |
| SCHEMBL26385 | 0.86 | THRB (0.60) | THRBAPPMEN1KMT2ATDP1 | |
| SCHEMBL29594423 | 0.86 | THRB (0.57) | THRBAPPMEN1KMT2ATDP1 | |
| SCHEMBL29883166 | 0.86 | THRB (0.60) | THRBAPPMEN1KMT2ATDP1 | |
| SCHEMBL29373132 | 0.86 | THRB (0.60) | THRBAPPMEN1KMT2ATDP1 | |
| SCHEMBL9406984 | 0.85 | THRB (0.53) | THRBAPPMEN1KMT2ATDP1 | |
| Amaranth SCHEMBL8618995 | 0.84 | THRB (0.72) | THRBAPPMEN1KMT2ATDP1 | |
| SCHEMBL8649053 | 0.84 | MPL (0.55) | THRBAPPMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242830-B2 | ENZYME AND FABRIC HUEING AGENT CONTAINING COMPOSITIONS | PROCTER & GAMBLE (US) | 2020-03-11 | — | — | EP | claimed |
| EP-3259340-A1 | FABRIC CARE COMPOSITION COMPRISING METATHESIZED UNSATURATED POLYOL ESTERS | The Procter and Gamble Company (US) | 2017-12-27 | — | — | EP | claimed |
| EP-3101110-A1 | ENZYME AND FABRIC HUEING AGENT CONTAINING COMPOSITIONS | The Procter and Gamble Company (US) | 2016-12-07 | — | — | EP | claimed |
| EP-3101111-A1 | ENZYME AND FABRIC HUEING AGENT CONTAINING COMPOSITIONS | The Procter and Gamble Company (US) | 2016-12-07 | — | — | EP | claimed |
| WO-2016134088-A1 | FABRIC CARE COMPOSITION COMPRISING METATHESIZED UNSATURATED POLYOL ESTERS | THE PROCTER & GAMBLE COMPANY (US) | 2016-08-25 | — | — | WO | claimed |
| US-8999912-B2 | Detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 2015-04-07 | — | — | US | claimed |
| EP-1483577-B1 | ABSORBING ORGANIC REAGENTS INTO DIAGNOSTIC TEST DEVICES BY FORMATION OF AMINE SALT COMPLEXES | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2015-01-07 | — | — | EP | claimed |
| US-8512418-B2 | Enzyme and fabric hueing agent containing compositions | THE PROCTER & GAMBLE COMPANY (US) | 2013-08-20 | — | — | US | claimed |
| US-20130196057-A1 | METHOD FOR PREPARING A SURFACE ENHANCED RAMAN SPECTROSCOPY PARTICLE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-08-01 | — | — | US | claimed |
| EP-2242830-B1 | ENZYME AND FABRIC HUEING AGENT CONTAINING COMPOSITIONS | PROCTER & GAMBLE (US) | 2013-03-13 | — | — | EP | claimed |
| US-20040162613-A1 | Cosmetic and reconstructive prosthesis containing a biologically compatible rupture indicator | TONABA HEALTHSCIENCE, LLC | 2004-08-19 | — | — | US | claimed |
| US-20030194346-A1 | Hydrogen peroxide and peracetic acid indicators and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2003-10-16 | — | — | US | claimed |
| WO-2003057262-A1 | HYDROGEN PEROXIDE AND PERACETIC ACID INDICATORS AND METHODS USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-07-17 | — | — | WO | claimed |
| US-6436419-B1 | Antimicrobial treatment of polymers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-08-20 | — | — | US | claimed |
| WO-2002059093-A1 | METHODS AND COMPOSITIONS FOR BINDING NUCLEIC ACID MOLECULES | GENESPAN CORPORATION (US) | 2002-08-01 | — | — | WO | claimed |
| EP-1115940-A1 | ANTIMICROBIAL TREATMENT OF POLYMERS | The Regents of the University of California (US) | 2001-07-18 | — | — | EP | claimed |
| WO-2000015897-A1 | ANTIMICROBIAL TREATMENT OF POLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-03-23 | — | — | WO | claimed |
| US-6020374-A | INSULIN MIMICS | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 2000-02-01 | — | — | US | claimed |
| US-5914806-A | Stable electrophoretic particles for displays | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1999-06-22 | — | — | US | claimed |
| US-5364466-A | Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-11-15 | — | — | US | claimed |