SCHEMBL1282001

SCHEMBL1282001

Ic1cccc2cccnc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.61
LMNA P02545 3/20 0.61
MMP2 P08253 2/20 0.61
TSHR P16473 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
CYP3A4 P08684 2/20 0.61
MAPT P10636 2/20 0.61
ALOX15 P16050 2/20 0.61
HTT P42858 2/20 0.61
CCR1 P32246 2/20 0.61
CCR5 P51681 2/20 0.61
CCR8 P51685 2/20 0.61
GMNN O75496 1/20 0.61
TP53 P04637 1/20 0.61
HSP90AA1 P07900 1/20 0.61
CYP2D6 P10635 1/20 0.61
MMP9 P14780 1/20 0.61
NFKB1 P19838 1/20 0.61
MMP8 P22894 1/20 0.61
THPO P40225 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23487640 0.80 LMNA (0.56) KDM4ELMNAMMP2TSHRTDP1
Phenanthroline SCHEMBL29354015 0.76 CCR1 (1.00) KDM4ELMNAMMP2TSHRTDP1
Phenanthroline SCHEMBL29367277 0.76 CCR1 (1.00) KDM4ELMNAMMP2TSHRTDP1
Phenanthroline SCHEMBL8312 0.76 CCR1 (1.00) KDM4ELMNAMMP2TSHRTDP1
Phenanthroline SCHEMBL8845760 0.76 CCR1 (1.00) KDM4ELMNAMMP2TSHRTDP1
SCHEMBL19001628 0.76 KDM4E (0.48) KDM4ELMNAMMP2TSHRTDP1
SCHEMBL18583712 0.76 LMNA (0.48) KDM4ELMNAMMP2TSHRTDP1
Phenanthroline SCHEMBL9046756 0.75 CCR1 (0.84) KDM4ELMNAMMP2TSHRTDP1
SCHEMBL1282008 0.75 CCR1 (0.75) KDM4ELMNAMMP2TSHRTDP1
SCHEMBL30184687 0.75 CCR1 (0.75) KDM4ELMNAMMP2TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113061143-B Metal silver-N-heterocyclic carbene polymer, preparation method and application thereof 湖北师范大学 2022-06-24 CN claimed
CN-113061143-A Metal silver-N-heterocyclic carbene polymer, preparation method and application thereof 湖北师范大学 2021-07-02 CN claimed
US-12351556-B2 Pyridin-2(1H)one derivatives, their preparation and their use for the treatment of pain INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2025-07-08 US disclosed
WO-2025129168-A1 TRIAZOLONE INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE AND THEIR THERAPEUTIC USES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2025-06-19 WO disclosed
US-20230371357-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-16 US disclosed
US-20230363260-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-20230354694-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, ELECTONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-02 US disclosed
US-20230337524-A1 ORGANOMETALLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-19 US disclosed
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed
US-11730053-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-15 US disclosed
US-11678498-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
EP-0363212-B1 Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components MITSUI TOATSU CHEMICALS (JP) 1995-01-04 EP disclosed
US-5204348-A Quinoline derivatives MITSUI TOATSU CHEMICALS INC. (JP) 1993-04-20 US disclosed
US-5112817-A Anticancer Drug Potentiators MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-05-12 US disclosed
EP-0363212-A2 Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-04-11 EP disclosed
EP-0088595-B1 CYANINE DYES FOR SENSITIZING SILVER HALIDE EMULSIONS TO INFRARED RADIATION AND PHOTOGRAPHIC ELEMENTS INCLUDING THEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-09-24 EP disclosed
US-4515888-A BASED ON 5-METHYL-6-METHOXYBENZOTHIAZOLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-07 US disclosed
EP-0088595-A2 Cyanine dyes for sensitizing silver halide emulsions to infrared radiation and photographic elements including them MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-09-14 EP disclosed
EP-0044184-A2 Blend of polyarylene sulfide and wholly aromatic polyester CELANESE CORPORATION (US) 1982-01-20 EP disclosed
US-4276397-A IMPROVED PROCESSABILITY TO FORM MOLDED ARTICLES CELANESE CORPORATION (US) 1981-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337524-A1 ORGANOMETALLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING THE SAME LAGE3, L1CAM, LEF1 KDM4E 665/4885LMNA 3945/4885MMP2 4840/4885
US-20230371357-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, CHRM1, FOXM1 KDM4E 3285/4885LMNA 2039/4885MMP2 4751/4885
US-12351556-B2 Pyridin-2(1H)one derivatives, their preparation and their use for the treatment of pain P2RX3, P2RX6, P2RX4 KDM4E 3414/4885LMNA 1014/4885MMP2 3015/4885
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS NOM1, MNS1, NOS1 KDM4E 1841/4885LMNA 3288/4885MMP2 4259/4885
US-20230354694-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, ELECTONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING DEVICE LAGE3, ELP1, EML4 KDM4E 1805/4885LMNA 4338/4885MMP2 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.