Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 16/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7827431 | 0.98 | ENPP1 (0.44) | ENPP1CRHR1HTR6KDM4EMEN1 | |
| SCHEMBL126427 | 0.80 | KDM4E (0.58) | HTR6KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL5716488 | 0.80 | ENPP1 (0.45) | ENPP1CRHR1HTR6 | |
| SCHEMBL38666647 | 0.79 | PIK3CG (0.50) | HTR6KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL7465690 | 0.75 | MEN1 (0.44) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7815444 | 0.70 | HTR6 (0.41) | ENPP1CRHR1HTR6KDM4EMEN1 | |
| SCHEMBL7827118 | 0.68 | ENPP1 (0.50) | ENPP1HTR6KDM4EALDH1A1MAPT | |
| SCHEMBL128480 | 0.68 | PIK3CG (0.42) | HTR6KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL7465074 | 0.67 | HTR6 (0.40) | HTR6KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL7459734 | 0.64 | ALDH1A1 (0.35) | KDM4EMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443890-B1 | OXIDATION COLOURING AGENT BASED ON BICYCLIC DEVELOPER COMPONENTS | HENKEL AG & CO KGAA (DE) | 2010-01-13 | — | — | EP | claimed |
| EP-1352636-B1 | Oxidation dyeing composition for keratin fibers comprising 2-chloro-6-methyl-3-aminophenol and an oxidation base, and dyeing method | OREAL (FR) | 2009-04-22 | — | — | EP | claimed |
| EP-1405627-B1 | Antipenetrating hair pretreatment composition based on polyethelenoxide polymer(s) and process using said composition for limiting skin penetration by colourants | OREAL (FR) | 2008-04-30 | — | — | EP | claimed |
| WO-2007071688-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, A PARTICULAR OXIDATION BASE AND A COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| WO-2007071686-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| US-7189267-B2 | Oxyethylenated based hair pre-treatment anti-penetration composition and method using such a composition for limiting the penetration of dyes into the skin | L'OREAL (FR) | 2007-03-13 | — | — | US | claimed |
| US-7077871-B2 | Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye | L'OREAL (FR) | 2006-07-18 | — | — | US | claimed |
| EP-1210931-B1 | Keratinic fibres dyeing composition | OREAL (FR) | 2006-04-05 | — | — | EP | claimed |
| EP-1299072-B1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING AN AMPHOTERIC POLYMER WITH FATTY CHAIN | OREAL (FR) | 2005-11-16 | — | — | EP | claimed |
| US-20040231071-A1 | Oxyethylenated based hair pre-treatent anti-penetration composition and method using such a composition for limiting the penetration of dyes into the skin | L'OREAL (FR) | 2004-11-25 | — | — | US | claimed |
| US-6342078-B1 | OXIDATION COLOR DYES FOR HAIR WITH METAPHENYLENEDIAMINE COUPLERS | L'OREAL, S. A. (FR) | 2002-01-29 | — | — | US | claimed |
| US-6312479-B1 | OXIDATION BASE; COUPLER CHOSEN FROM 2-AMINO-3-HYDROXYPYRIDINES AND ACID-ADDITION SALTS THEREOF; A 2-ELECTRON OXIDOREDUCTASE; AND A DONOR FOR SAID ENZYME. | L'OREAL S.A. (FR) | 2001-11-06 | — | — | US | claimed |
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | claimed |
| US-20010032368-A1 | Dye compositions comprising at least one nonionic compound and uses thereof | L'OREAL S.A. (FR) | 2001-10-25 | — | — | US | claimed |
| US-6306181-B1 | FOR DYEING HUMAN HAIR | L'OREAL (FR) | 2001-10-23 | — | — | US | claimed |
| US-6277156-B1 | OXIDATION BASE ARE PARAPHENYLENEDIAMINES, DOUBLE BASES; PYRAZOLO(1,5-A)PYRIMIDINES ORTHO-AMINOPHENOLS; DIAMINOPYRIDINES | L'ORéAL S.A. (FR) | 2001-08-21 | — | — | US | claimed |
| US-6241784-B1 | COSMETICS OR SKIN COMPOSITION FOR TREATING FIBERS | L'OREAL S.A. (FR) | 2001-06-05 | — | — | US | claimed |
| US-6228129-B1 | OXIDATION BASE, CATIONIC DIRECT DYE AND AN ENZYME OF 2-ELECTRON OXIDOREDUCTASES IN THE PRESENCE OF A DONOR FOR THE ENZYME | L'OREAL S.A. (FR) | 2001-05-08 | — | — | US | claimed |
| US-6152967-A | COMPOSITION FOR HAIR DYEING COMPRISING AT LEAST ONE OXIDATION BASE AND BILIRUBIN OXIDASE | L'OREAL (FR) | 2000-11-28 | — | — | US | claimed |
| US-6090159-A | READY-TO-USE OXIDATION DYEING COMPOSITION COMPRISING AN OXIDATION BASE, SARCOSINE OXIDASE AS OXIDIZER, AND AT LEAST ONE DONOR FOR THE ENZYME; STRONGER COLORATION, NO BLEACHING | L'OREAL (FR) | 2000-07-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | KRT18, FH, FGB | ENPP1 4275/4885CRHR1 2033/4885HTR6 2997/4885 |
| US-20040231071-A1 | Oxyethylenated based hair pre-treatent anti-penetration composition and method using such a composition for limiting the penetration of dyes into the skin | KRT18, CUTA, COL14A1 | ENPP1 2128/4885CRHR1 4137/4885HTR6 1605/4885 |
| US-20010032368-A1 | Dye compositions comprising at least one nonionic compound and uses thereof | KRT18, AKR1B10, NDUFA10 | ENPP1 4798/4885CRHR1 2499/4885HTR6 2883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.