Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 4/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475235 | 0.78 | ACHE (0.36) | ACHEDRD2DRD4DRD3HRH3 | |
| SCHEMBL1477211 | 0.77 | MAOA (0.51) | ACHEDRD2DRD4DRD3HRH3 | |
| SCHEMBL1477451 | 0.71 | DRD2 (0.40) | ACHEDRD2DRD4BCHE | |
| SCHEMBL1475625 | 0.71 | MAOA (0.47) | ACHEDRD2DRD4DRD3 | |
| SCHEMBL1475924 | 0.70 | SIGMAR1 (0.52) | — | |
| SCHEMBL1476560 | 0.70 | GRIN2B (0.39) | ACHEDRD4KDM5B | |
| SCHEMBL1475948 | 0.70 | FAAH (0.42) | ACHEDRD2DRD4DRD3HRH3 | |
| SCHEMBL1475280 | 0.70 | CHRM2 (0.40) | ACHEDRD2DRD4DRD3BCHE | |
| SCHEMBL1476139 | 0.69 | DCPS (0.39) | KDM5B | |
| SCHEMBL1475267 | 0.69 | DCPS (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915274-B2 | Nitrogen containing heterocyclic compounds and medicines containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-03-29 | — | — | US | disclosed |
| US-20070293496-A1 | Nitrogen containing heterocyclic compounds and medicines containing the same | OZAKI FUMIHIRO | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293496-A1 | Nitrogen containing heterocyclic compounds and medicines containing the same | XDH, NQO1, CYP1A1 | ACHE 1608/4885DRD2 608/4885DRD4 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.